薛婧 - 中国医学科学院医学实验动物研究所 -

个人简介

2006年在首都医科大学获得学士学位，2011年在北京协和医学院基础医学研究所获免疫学博士学位。

研究领域

艾滋病的致病机制和抗感染免疫研究。1、艾滋病动物模型创制、应用及致病机制研究；2、病原感染宿主细胞的免疫调节机制、细胞凋亡机制及信号通路研究；3、宿主免疫与HIV/SIV的相互作用及其与疾病进程和临床转归之间的关系。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1、Chong H(#), Xue J(#), Zhu Y(#), Cong Z, Chen T, Wei Q, Qin C*, He Y*. Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques.PLoS Pathog. 2019 Feb 4;15(2):e1007552. 2、Chong H(#), Xue J(#), Zhu Y, Cong Z, Chen T, Guo Y, Wei Q, Zhou Y, Qin C*, He Y*.Design of Novel HIV-1/2 Fusion Inhibitors with High Therapeutic Efficacy in Rhesus Monkey Models.J Virol. 2018 Jul 31;92(16). 3、Li KL, Cong Z, Peng ZY, Chen T, Xue J*, Wei Q*.CD45RO regulates the HIV-1 gp120-mediated apoptosis of T cells by activating Lck.Biol Chem. 2018 May 24;399(6):583-591. 4、Chong H(#), Xue J(#), Xiong S, Cong Z, Ding X, Zhu Y, Liu Z, Chen T, Feng Y, He L, Guo Y, Wei Q, Zhou Y, Qin C*, He Y*. A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity. J Virol. 2017 May 12;91(11). 5、He H(#), Xue J(#), Wang W, Liu L, Ye C, Cong Z, Kimata J, Qin C*, Zhou P*. Efficient Transduction of Human and Rhesus Macaque Primary T Cells by a Modified Human Immunodeficiency Virus Type 1-Based Lentiviral Vector. Hum Gene Ther. 2017 Mar;28(3):271-285. 6、Xue J, Fu C, Cong Z, Peng L, Peng Z, Chen T, Wang W, Jiang H, Wei Q*, Qin C*. Galectin-3 promotes caspase-independent cell death of HIV-1-infected macrophages. FEBS J. 2017 Jan;284(1):97-113. 7、Xue J(#), Gao XQ(#), Fu CY, Cong Z, Jiang H, Wang W, Chen T, Wei Q*, Qin C*. Regulation of galectin-3-induced apoptosis of Jurkat cells by both O-glycans and N-glycans on CD45. FEBS Lett. 2013 Dec 11;587(24):3986-94. 8、Xue J, Zhu LP, Wei Q. IgG-Fc N-glycosylation at Asn297 and IgA O-glycosylation in the hinge region in health and disease.Glycoconj J. 2013 Nov;30(8):735-45. 9、Xue J(#), Cong Z(#), Xiong J, Wang W, Jiang H, Chen T, Wu F, Liu K, Su A, Ju B, Chen Z, Couto MA, Wei Q*, Qin C*. Repressive effect of primary virus replication on superinfection correlated with gut-derived central memory CD4(+) T cells in SHIV-infected Chinese rhesus macaques. PLoS One. 2013 Sep 2;8(9):e72295. 10、Xue J, Zhao Q, Zhu LP, Zhang W. Deglycosylation of FcαR at N58 increases its binding to IgA. Glycobiology. 2010 Jul, 20(7):905-15.

学术兼职

中国实验动物学会，理事。《中国实验动物学报》、《中国比较医学杂志》两刊通讯编委