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研究领域

生物材料与细胞的相互作用关系; 靶向药物与纳米工程技术; 药物化学。

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1. Yu, B.; Li, X.; Zheng, W.; Feng, Y.; Wong, Y.-S.; Chen, T., pH-responsive cancer-targeted selenium nanoparticles: a transformable drug carrier with enhanced theranostic effects. Journal of Materials Chemistry B 2014, 2 (33), 5409-5418. 2. Yu, B.; Zhang, Y. B.; Zheng, W. J.; Fan, C. D.; Chen, T. F., Positive Surface Charge Enhances Selective Cellular Uptake and Anticancer Efficacy of Selenium Nanoparticles. Inorg. Chem. 2012, 51 (16), 8956-8963. 3. Yu, B.; Chen, T. F.; Yang, F.; Liu, W.; Li, Y. H.; Zheng, W. J., Chitosan as Morphology-directing Agent for the Preparation of Multiarmed Selenium/Carbon Coaxial Nanorods. Chem. Lett. 2011, 40 (3), 242-243. 4. Wu, H. L.; Zhu, H. L.; Li, X. L.; Liu, Z. M.; Zheng, W. J.; Chen, T. F.; Yu, B.; Wong, K. H., Induction of Apoptosis and Cell Cycle Arrest in A549 Human Lung Adenocarcinoma Cells by Surface-Capping Selenium Nanoparticles: An Effect Enhanced by Polysaccharide-Protein Complexes from Polyporus rhinocerus. J. Agric. Food Chem. 2013, 61 (41), 9859-9866. 5. Zheng, J. S.; Zheng, S. Y.; Zhang, Y. B.; Yu, B.; Zheng, W. J.; Yang, F.; Chen, T. F., Sialic acid surface decoration enhances cellular uptake and apoptosis-inducing activity of selenium nanoparticles. Colloid Surf. B-Biointerfaces 2011, 83 (1), 183-187. 6. Luo, Z.; Yu, L.; Yang, F.; Zhao, Z.; Yu, B.; Lai, H.; Wong, K. H.; Ngai, S. M.; Zheng, W.; Chen, T., Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase. Metallomics 2014, 6 (8), 1480-90.

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