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个人简介

2017.1—今,中科院昆明植物研究所副研究员 2010.9—2016.12,中科院昆明植物研究所助理研究员 2005.9—2010.7,兰州大学,细胞生物学,博士 2001.9—2005.7,兰州大学,生命科学学院,学士

研究领域

植物天然产物生物功能、生物合成与合成生物学研究:主要运用生物化学、分子生物学等手段,开展结构新颖天然产物的生物功能与生物合成研究,解析其生源途径并发现新颖酶催化机制,在此基础上开展重要活性分子的合成生物学研究

近期论文

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1. Yan Liu#, Shuxi Jing#, Shihong Luo, Shenghong Li*. Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis. Natural Product Reports, 2019, 36: 626-665. 2. Yan Liu#, Shihong Luo, Axel Schmidt, Guodong Wang, Guiling Sun, Marcus Grant, Ce Kuang, Minjie Yang, Shuxi Jing, Chunhuan Li, Bernd Schneider, Jonathan Gershenzon, Shenghong Li*. A geranylfarnesyl diphosphate synthase provides the precursor for sesterterpenoid (C25) formation in the glandular trichomes of the mint species Leucosceptrum canum. Plant Cell, 2016, 28: 804–822. (Cover Article) 3. Ting Tang#, Chunhuan Li#, Desen Li, Shuxi Jing, Juan Hua, Shihong Luo, Yan Liu*, Shenghong Li*. Peltate glandular trichomes of Colquhounia vestita harbor diterpenoid acids that contribute to plant adaptation to UV radiation and cold stresses. Phytochemistry, 2020, 172: 112285. 4. Fei Luo#, Yi Ling, Desen Li, Ting Tang, Yanchun Liu, Yan Liu*, Shenghong Li*. Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana. Phytochemistry, 2019, 162: 121-128. 5. Yi Ling#, Linlin Teng, Juan Hua, Desen Li, Shihong Luo, Yanchun Liu, Yan Liu*, Shenghong Li*. Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis. Chinese Journal of Natural Medicines, 2019, 17: 0892-0899. 6. Chaojiang Xiao#, Yanchun Liu, Shihong Luo, Juan Hua, Yan Liu*, Shenghong Li*. Localization of Two bioactive labdane diterpenoids in the peltate glandular trichomes of Leonurus japonicas by laser microdissection coupled with UPLC-MS/MS. Phytochemical Analysis, 2017, 28: 404-409. 7. Yanyun Tan#, Desen Li, Juan Hua, Shihong Luo, Yan Liu*, Shenghong Li*, Localization of a defensive volatile 4-hydroxy-4-methylpentan-2-one in the capitate glandular trichomes of Oenothera glazioviana. Plant Diversity, 2017, 39: 154-159. 8. Caiguo Zhang#, Yan Liu*. Targeting cancer with sesterterpenoids: the new potential antitumor drugs. Journal of Natural Medicines, 2015, 69: 255-266. 9. Chunhuan Li#, Yan Liu#, Juan Hua, Shihong Luo, Shenghong Li*. Peltate glandular trichomes of Colquhounia seguinii harbor new defensive clerodane diterpenoids. Journal of Integrative Plant Biology, 2014, 56: 928-940. (Co-first author) 10. Kai Guo#, Yan Liu, Shihong Luo, Yanchun Liu, Desen Li, Wenyuan Li, Shenghong Li*. Detoxification of plant aromatic abietanoids via cleavage of the benzene ring into 11,12-seco-diterpene polyenes by a specialist insect of Leucosceptrum canum. Organic Letters, 2020, 22: 126-129. 11. Wenyuan Li#, Yan Liu, Yutian Lin, Yanchun Liu, Kai Guo, Xiaonian Li, Shihong Luo*, Shenghong Li*. Antibacterial harziane diterpenoids from a fungal symbiont Trichoderma atroviride isolated from Colquhounia coccinea var. mollis. Phytochemistry, 2020, 170: 112198. 12. Kai Guo#, Yanchun Liu, Yan Liu, Shihong Luo, Wenyuan Li, Xiaonian Li, Shenghong Li*, Diversified abietane family diterpenoids from the leaves of Leucosceptrum canum and their cytotoxic activity. Phytochemistry, 2019, 157: 43-52. 13. Juan Hua#, Yan Liu, Chaojiang Xiao, Shuxi Jing, Shihong Luo*, Shenghong Li*. Chemical profile and defensive function of the latex of Euphorbia peplus. Phytochemistry, 2017, 136: 56-64. 14. Ying Wang#, Shihong Luo, Juan Hua, Yan Liu, Shuxi Jing, Xiaonian Li, Shenghong Li*. Capitate glandular trichomes of Paragutzlaffia henryi harbor new phytotoxic labdane diterpenoids. Journal of Agricultural and Food Chemistry, 2015, 63: 10004-10012. 15. Shuxi Jing#, Shihong Luo, Chunhuan Li, Juan Hua, Yanli Wang, Xuemei Niu, Xiaonian Li, Yan Liu, Chunshuai Huang, Ying Wang, Shenghong Li*. Biologically active dichapetalins from Dichapetalum gelonioides. Journal of Natural Products, 2014, 77: 882?893. 16. Shihong Luo#, Cedric L. Hugelshofer, Juan Hua, Shuxi Jing, Chunhuan Li, Yan Liu, Xiaonian Li, Xu Zhao, Thomas Magauer, Shenghong Li*. Unraveling the metabolic pathway in Leucosceptrum canum by isolation of new defensive leucosceptroid degradation products and biomimetic model synthesis. Organic Letters, 2014, 16: 6416?6419. 17. Chunhuan Li#, Shuxi Jing, Shihong Luo, Wei Shi, Juan Hua, Yan Liu, Xiaonian Li, Bernd Schneider, Jonathan Gershenzon, Shenghong Li*. Peltate glandular trichomes of Colquhounia coccinea var. mollis harbor a new class of defensive sesterterpenoids, Organic Letters, 2013, 15: 1694-1697. 18. Shihong Luo#, Juan Hua, Xuemei Niu, Yan Liu, Chunhuan Li, Yanying Zhou, Shuxi Jing, Xu Zhao, Shenghong Li*. Defense sesterterpenoid lactones from Leucosceptrum canum. Phytochemistry, 2013, 86: 29-35. 19. Shihong Luo#, Juan Hua, Chunhuan Li, Yan Liu, Xiaonian Li, Xu Zhao, Shenghong Li*. Unusual antifeedant spiro-sesterterpenoid from the flowers of Leucosceptrum canum. Tetrahedron Letters, 2013, 54: 235-237. 20. Shihong Luo#, Yan Liu, Juan Hua, Xuemei Niu, Shuxi Jing, Xu Zhao, Bernd Schneider, Jonathan Gershenzon, Shenghong Li*. Unique proline–benzoquinone pigment from the colored nectar of “Bird’s Coca Cola Tree” functions in bird attractions. Organic Letters, 2012, 14: 4146-4149. 21. Shihong Luo#, Juan Hua, Chunhuan Li, Shuxi Jing, Yan Liu, Xiaonian Li, Xu Zhao, Shenghong Li*. New antifeedant c20 terpenoids from Leucosceptrum canum. Organic Letters, 2012, 14: 5768-5771.

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