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个人简介

2004年7月获华东师范大学学士学位;2010年7月获中科院上海生科院博士学位后,留所工作一年; 2011年10月至2016年7月在美国西南医学中心Sean J. Morrison实验室从事博士后研究,获Leukemia & Lymphoma Society Fellowship资助;2016年8月入职中科院生化与细胞所,任研究员,研究组长,博士生导师

研究领域

造血干细胞与白血病

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Yi Jacky Peng, Hua Yu, Xiaoxin Hao, Wenjie Dong, Xiujuan Yin, Minghui Lin, Junke Zheng and Bo O. Zhou. 2018. Luteinizing hormone signaling restricts hematopoietic stem cell expansion during puberty. EMBO J doi: 10.15252/embj.201898984 Qi Jason Yao, Lina Sang, Minghui Lin, Xiujuan Yin, Wenjie Dong, Yuping Gong and Bo O. Zhou. 2018. Mettl3-Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells. Cell Res doi: 10.1038/s41422-018-0062-2 Bo O. Zhou*, Hua Yu, Rui Yue, Jonathan J. Rios, Olaia Naveiras and Sean J. Morrison*. 2017. Bone marrow adipocytes promote the regeneration of stem cells and hematopoiesis after irradiation by secreting SCF. Nat Cell Biol 19, 851-903 (Cover story, *co-corresponding authors) Bo O. Zhou, Linheng Li, Meng Zhao. 2017. “The evolvement of hematopoietic stem cell niches” in Advances in Stem Cells and Their Niches, volume 1. Elsevier, 2017 (Book chapter) Christopher N. Inra#, Bo O. Zhou#, Melih Acar, Malea M. Murphy, James Richardson, Zhiyu Zhao, Sean J. Morrison. 2015. A perisinusoidal niche for extramedullary haematopoiesis in the spleen. Nature (Article) 527:466-471. (#co-first authors) Bo O. Zhou#, Lei Ding#, Sean J. Morrison. 2015. Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1. eLife 4:e05521.(#co-first authors) Bo O. Zhou, Rui Yue, Malea M. Murphy, James Peyer, Sean J. Morrison. 2014. Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow. Cell Stem Cell 15:154-168. Bo O. Zhou, Jin-Qiu Zhou. 2011. Recent transcription-induced histone H3 lysine 4 (H3K4) methylation inhibits gene reactivation. J Biol Chem 286:34770-34776. Bo O. Zhou, Shan-Shan Wang, Yang Zhang, Xiao-Hong Fu, Wei Dang, Brian A. Lenzmeier, Jin-Qiu Zhou. 2011. Histone H4 lysine 12 acetylation regulates telomeric heterochromatin plasticity in Saccharomyces cerevisiae. PLoS Genet 7:e1001272. Bo O. Zhou, Shan-Shan Wang, Lu-Xia Xu, Fei-Long Meng, Yao-Ji Xuan, Yi-Min Duan, Jian-Yong Wang, Hao Hu, Xianchi Dong, Jianping Ding, Jin-Qiu Zhou. 2010. SWR1 complex poises heterochromatin boundaries for antisilencing activity propagation. Mol Cell Biol 30:2391-2400. Shan-Shan Wang, Bo O. Zhou*, Jin-Qiu Zhou*. 2011. Histone H3 lysine 4 hypermethylation prevents aberrant nucleosome remodeling at the PHO5 promoter. Mol Cell Biol 31:3171-3181.(*co-corresponding authors) Deng-Hong Zhang#, Bo O. Zhou#, Yu Huang, Lu-Xia Xu, Jin-Qiu Zhou. 2006. The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity. Nucleic Acids Res 34:1393-1404.(#co-first authors)

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