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X Zhou, WY Li S Wang, P Zhang, Q Wang, J Xiao, C Zhang, X Zheng, X Xu, S Xue, L Hui, H Ji, B Wei#, H Wang#. YAP aggravates inflammatory bowel disease (IBD) via regulating M1/M2 macrophage polarization and gut microbial homeostasis. Cell Reports, 2019
Y Lu*, Y Qiu*, P Chen, H Chang, L Guo, F Zhang, L Ma, C Zhang, X Zheng, J Xiao, R Zhong, L Han, X Xu, Y Zhang, D Li, G Zhong, R Boyton, Y Huang, Y He, R Hu#, B Wei#, H Wang# The ER-localised Hrd1 ubiquitinates and inactivates Usp15 to promote TLR4-induced inflammation during bacterial infection, Nature Microbiology, 2019 Accepted in principle
T Zhou#, MC Luo, W Cai, SY Zhou, DY Feng, CD Xu, H. Wang#. Runt-related transcription factor 1 (RUNX1) promotes TGF-β-induced renal tubular epithelial-to-mesenchymal transition (EMT) and renal fibrosis through the PI3K subunit p110δ. EBioMedicine, 2018.31:217-225
XY Xu, L Han, G. Zhao, SJ Xue, Y Gao, J Xiao, ZY Wu, JP Ding, B Wei, RG Hu, H Wang. LRCH1 interferes with DOCK8-Cdc42 module-induced T cell migration and ameliorates multiple sclerosis. J Exp Med, 2017; 214(1):209-226.
SJ Xue, C Liu, XJ Sun, WY Li, C Zhang, X Zhou, Y Lu, J Xiao, CY Li, XY Xu, B Sun, GL Xu, H Wang. TET3 inhibits IFN-I production independent of DNA demethylation. Cell Reports, 2016;16:1-10
W Li, J Xiao, X Zhou, M Xu, C Hu, X Xu, Y Lu, C Liu, S Xue, L Nie, H Zhang, Z Li, Y Zhang, F Ji, L Hui, W Tao, B Wei# and H Wang#. STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma. The Journal of Clinical Investigation, 2015; 125(11):4239-54
Li C, Li W, Xiao J, Jiao S, Sheng C, Rudd CE, Wei B, Wang H#. ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy. EMBO Mol Med, 2015: e201404578
Jiao S, Li C, Wang G, Gao Y, He X, Liu C, Zhang G, Wei B, Chen H, Wang H#. The immune adaptor ADAP regulates reciprocal TGF-β1-integrin crosstalk to protect from H5N1 influenza virus infection. PLoS Pathogens, 2015, 11(4):e1004824
Fu X, Xiao J, Wei Y, Guo H, Li S, Liu Y, Yin J, Li D, Wang H#, Hu P#. Combination of four pro-inflammatory cytokines promotes long term muscle stem cell expansion in vitro. Cell Research, 2015, May 15. doi: 10.1038/cr.2015.58 (Cover Story)
Zhang Y, Lu Y, Ma L, Jiao S, Chen J, Gao Y, Liu C, Duan Z, Li D, He Y, Wei B#, Wang H# Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR-NF-κB signaling and protects from endotoxin shock Immunity, 2014, 40: 501-514 (Cover Story)
Huang Y, Jiao S, Tao X, Tang Q#, Jiao W, Xiao J, Xu X, Zhang Y, Liang G, Wang H # Met-CCL5 represents an immunotherapy strategy to ameliorate rabies virus infection. J Neuroinflammation 2014,11:146
Zhang M, Zhou H, Zheng C, Xiao J, Zuo E, Liu W, Xie D, Shi Y, Wu C, Wang H, Li D, Li J. The Roles of Testicular C-kit Positive Cells in De novo Morphogenesis of Testis. Sci Rep 2014; 4: 5936; 1-11
Yu T, Tao Y, Yang1 M, Chen P, Gao X, Zhang Y, Zhang T, Chen Z, Hou J, Zhang Y, Ruan K, Wang H, Hu R. Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Res. 2014:1-17
Wei B*, Han L*, Abbink T, Elisabetta G, Lim D, Thaker YR, Gao W, Zhai R, Wang J, Lever A, Jolly C, Wang H# and Rudd CE#. Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors. Retrovirology, 2013:10:101
Zhang Y and Wang H#. Integrin signaling and function in immune cells. Immunology, 2012;4(135):267-75
Li C, Xu X, Wang H# and Wei B#. PD-1 and CTLA-4 mediated inhibitory signaling for T cell exhaustion during chronic viral infections. Journal of Clinical & Cellular Immunology, 2012, S7-10.
Yao Y, Wang Y, Chen F, Huang Y, Zhu S, Leng Q, Wang H, Shi Y, Qian Y. NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens. Cell Res. 2012;22(5):836-47.
Wang H#, Lim D and Rudd CE. Integrin signaling and immunopathology Semin Immunopathol 2010;32(2):173-82
Raab M, Wang H, Lu Y, Smith X, Wu Z, Strebhardt K, Ladbury JE, Rudd CE. T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes. Immunity 2010;32(4):541-56.
Wang H, Lv Y and Rudd CE. SKAP1 is dispensable for chemokine induced T-cell migration. Immunol Letters 2010:128(2):148-53.
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