个人简介
1995 -1999，北京师范大学，学士
1999 -2002，中国科学院上海药物研究所，硕士
2002 -2008，美国Brandeis大学，博士
2008 -2009，美国Brandeis大学，博士后
2009 -2012，美国哈佛医学院，博士后
2012-2014，中科院上海生科院生化与细胞所，蛋白质中心（筹），核磁应用主管
2014年起任中科院上海生科院生化与细胞所研究员
研究领域
核磁共振(NMR)方法为主，结合其它的结构生物学手段来测定膜蛋白结构，研究它们的功能与分子机制。膜蛋白是一类在生命活动中非常重要的蛋白，但是目前膜蛋白三维结构的研究远远落后于水溶性蛋白。而在溶液里利用核磁共振技术测膜蛋白的结构，是攻克难以结晶的膜蛋白的一个重要技术。同时核磁技术在观察蛋白的动态变化过程上具有其独特的优势。目前课题组的主要研究内容是解析线粒体中关键膜蛋白及其复合物的三维结构，并基于结构进行功能分析，提出并验证这些蛋白质发挥生理功能或引发代谢疾病的分子机制
近期论文
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Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, YaseminSancak, Andrew L. Markhard, ZenonGrabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha & James J. Chou*, Nature, 2016, 533(7602), 269-73
Linlin Zhao, Shuqing Wang, Lingyu Du, Jyoti Dev, Liujuan Zhou, Zhijun Liu, James J. Chou*, Bo OuYang*, Protein & Cell, 2016, 7(4),300-304
Changqing Run, Qin Yang, Zhijun Liu, Bo OuYang*, James J. Chou*, Structure, 2015, 23,1394-403
Jyoti Dev, Sven Brüschweiler, Bo OuYang, James J. Chou*, J Biomol NMR, 2015, 61, 369-78
Bo OuYang, James J. Chou*, Biochimica et Biophysica Acta, 2014, 1838,1058-1067
Bo OuYang, Shiqi Xie, Marcelo J. Berardi, Xinhao Zhao, Jyoti Dev, Wenjing Yu, Bing Sun & James J. Chou, "Unusual architecture of the p7 channel from hepatitis C virus", Nature, 2013, 498, 521-526
Eliana K. Asciutto, Jeffry D. Madura, Susan S. Pochapsky, Bo OuYang, Thomas C. Pochapksy, "Structural and dynamic implications of an effector-induced backbone amide cis-trans isomerization in cytochrome P450cam", Journal of Molecular Biology, 2009, 388, 801-814
Susan S. Pochapsky, Marina Dang, Bo OuYang, Alana K. Simorellis and Thomas C. Pochapsky, "Redox-dependent dynamics in cytochrome P450cam", Biochemistry, 2009, 48, 4254–4261
Bo OuYang, Susan S. Pochapsky, Marina Dang and Thomas C. Pochapsky, "A functional proline switch in cytochrome P450cam", Structure 2008, 16, 916-923.
Yoshitomo Hamuro, Kathleen S. Molnar, Stephen J. Coales, Bo OuYang, Alana Simorellis and Thomas C. Pochapsky, "Tandem mass spectrometry for investigation of backbone dynamics of oxidized and reduced cytochrome P450cam" Journal of Inorganic Biochemistry, 2008, 102, 364-370
Bo OuYang, Susan S. Pochapsky, Gina M. Pagani, and Thomas C. Pochapsky, "Specific effects of potassium ion binding on wild-type and L358P cytochrome P450cam", Biochemistry, 2006, 45, 14379-14388
Margret Sauter, Rene Lorbiecke, Bo OuYang, Thomas C. Pochapsky and Guillaume Rzewuski, "The immediate-early ethylene response gene OsARD1 encodes an Acireductone dioxygenase involved in recycling of the ethylene precursor S-adenosylmethionine", Plant Journal, 2005, 44, 718-729
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