个人简介
2000/09-2004/07 复旦大学药学院 学士
2004/09-2009/07 中科院上海药物研究所，药物化学 博士
2010/08-现在 中国科学院上海有机化学研究所 助研、副研究员
近期论文
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1)Huang, Shao-Xu; Li, Hui-Yuan; Liu, Jun-Yan; Morisseau, Christophe; Hammock, Bruce D.; Long, Ya-Qiu*. Incorporation of Piperazino Functionality into 1,3-Disubstituted Urea as the Tertiary Pharmacophore Affording Potent Inhibitors of Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties. Journal of Medicinal Chemistry, 53(23), 8376-8386, 2010.
2)Huang, Shao-Xu; Ding Kuiling*. Asymmetric bromoamination of chalcones with a privileged N,N'-dioxide/scandium(III) catalyst. Angewandte Chemie International Edition. 50(34), 7734-7736, 2011. (Highlight).
3)Huang, Shao-Xu; Cao, Bin; Morisseau, Christophe; Tin, Yi; Hammock, Bruce D.; Long, Ya-Qiu*. Structure-based optimization of the piperazino-containing 1,3-disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase. MedChemComm, 3(3), 379-384, 2012.
4)黄少胥; 王勇; 龙亚秋*. 人类可溶性环氧化物水解酶抑制剂的研究进展. 《有机化学》, 05期, 877-888, 2012.
5)Long, Ya-Qiu*; Huang, Shao-Xu; Zawahir, Zahrah; Xu, Zhong-Liang; Li, Huiyuan; Sanchez, Tino W.; Zhi, Ying; De Houwer, Stephanie; Christ, Frauke; Debyser, Zeger; Neamati, Nouri*. Design of Cell-Permeable Stapled Peptides as HIV-1 Integrase Inhibitors. Journal of Medicinal Chemistry, 56(13), 5601–5612, 2013.
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