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研究领域

药物化学、有机分子荧光探针。

近期论文

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1. Ruibing An, Datong Zhang,*, Yan Chen, Yue-zhi Cui. A “turn-on” fluorescent and colorimetric sensor for selective detection of Cu2+ in aqueous media and living cells. Sensors and Actuators B, 222 (2016) 48–54. 2. Peng Wei, Datong Zhang*, Zhigang Gao, Wenqing Cai, Weiren Xu, Lida Tang and Guilong Zhao*. Iodine Monochloride (ICl) as a Highly Efficient, Green Oxidant for the Oxidation of Alcohols to Corresponding Carbonyl Compounds. Synthetic Communications, 2015, 45(12):1457-1470. 3.Datong Zhang*, Yuntong Ma, Ruibing An. New colorimetric chemosensor based on rhodamine hydrazide to detect Cu2+ ions by naked eye. Res Chem Intermed., 2015, 41(8): 5059-5069. 4. Gao Zhigang, Zhang Datong*, Wei Peng, Wang Zhe, Xie Yafei, Liu Yuqiang, Xu Weiren, Tang Lida, Zhao Guilong*. A facile convergent synthetic procedure for 3-deoxydapagliflozin as SGLT2 inhibitor. Chin. J. Org. Chem, 2014, 34, 1829-1839. 5. Datong Zhang*, Yuntong Ma, Yu Liu and Zhao-Peng Liu. Synthesis of sulfonylhydrazone- and acylhydrazone-substituted 8-ethoxy-3-nitro-2H-chromenes as potent antiproliferative and apoptosis inducing agents. Arch. Pharm. Life Sci. 2014, 347, 576-588. 6. Kai Liu, Datong Zhang, Jeremy Chojnacki, Yuhong Du, Haian Fu, Steven Grant and Shijun Zhang. Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma. Organic & Biomolecular Chemistry, 2013, 11,4757-4763. 7. Datong Zhang*, Lingyan Huo, Laichun Lu, Qiong Yu, Jianwu Wang, Yanyan Yang. Synthesis and preliminary antibacterial evaluation of hydroxamic acid and N-formyl hydroxylamine derivatives bearing oxazole ring. Medicinal Chemistry Research, 2013, 22(3):1426-1437. 8. Datong Zhang*, Guangtian Wang, Guilong Zhao,Weiren Xu, Lingyan Huo. Synthesis and Cytotoxic Activity of Novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives . European Journal of Medicinal Chemistry, 2011,46 (12): 5868-5877 9.Datong Zhang*, Guangtian Wang, Chubing Tan*, Weiren Xu, Yuan Pei and Lingyan Huo. Synthesis and biological evaluation of 3-(1H-indol-3-yl)pyrazole-5-carboxylic acid derivatives. Archives of Pharmacal research, 2011, 34(3): 343-355. 10.Datong Zhang*, Jiong Jia, Lijuan Meng, Weiren Xu, Lida Tang, and Jianwu Wang. Synthesis and Preliminary Antibacterial Evaluation of 2-Butyl Succinate-based Hydroxamate Derivatives Containing Isoxazole Rings. Archives of Pharmacal research, 2010, 33(6):831-842 11. Datong Zhang, Zongheng Wang, Weiren Xu, Fanggang Sun, and Jianwu Wang. Design,Synthesis and Antibacterial Activity of Novel Actinonin Derivatives Containing Benzimidazole Heterocycles. European Journal of Medicinal Chemistry, 2009,44 (5): 2202-2210 .

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