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个人简介

2013年毕业于中国科学院大连化学物理研究所分析化学专业,指导教师邹汉法研究员。2013年留所工作,并通过了大连化学物理研究所优秀青年人才项目,破格提拔为副研究员,2018年任研究员。

研究领域

主要研究方向为蛋白质糖基化分析,包括糖链的高选择性富集、糖基化位点占有率高准确度分析和位点特异性糖型高效解析

近期论文

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Hongqiang Qin#, Kai Cheng#, Jun Zhu#, Jiawei Mao, Fangjun Wang, Mingming Dong, Rui Chen, Zhimou Guo, Xinmiao Liang, Mingliang Ye, Hanfa Zou, Proteomics Analysis of O-GalNAc Glycosylation in Human Serum by an Integrated Strategy, Anal. Chem., 2017, 89, 1469-1476. (Co-first author). Xuefang Dong#, Hongqiang Qin#, Jiawei Mao, Dongping Yu, Xiuling Li, Aijin Shen, Jingyu Yan, Long Yu, Zhimou Guo, Mingliang Ye, Fanfa Zou, Xinmiao Liang, In-depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge, Anal. Chem., 2017, 89, 3966-3972. (Co-first author). Jian Wu#, Hongqiang Qin#, et al. Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer, Oncotarget, 2016, 7, 18, 25315-25327. (Co-first author). Junfeng Huang, Hongqiang Qin, et al. A peptide N-terminal protection strategy for comprehensive glycoproteome analysis using hydrazide chemistry based method. Sci. Report, 2015, 5, 10164, 1-15. Junfeng Huang, Hongqiang Qin, et al. In Situ Sample Processing Approach (iSPA) for Comprehensive Quantitative Phosphoproteome Analysis, J. Proteome Res., 2014, 13, 3896-3904. Ruibin Li, Zhaoxia Ji, Hongqiang Qin, et al. Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome, ACS Nano, 2014, 8, 10280-10292. Hongqiang Qin, Zhengyan Hu, et al. Facile preparation of ordered mesoporous silica–carbon composite nanoparticles for glycan enrichment Chem. Commun., 2013, 49, 5162-5165. Zhichao Xiong, Hongqiang Qin, et al. Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides Chem. Commun., 2013, 49, 9284-9286. Hao Wan, Hongqiang Qin, et al. Facile synthesis of yolk- shell magnetic mesoporous carbon microspheres for efficient enrichment of low abundance peptides, Nanoscale, 2013, 5, 10936–10944. Hongqiang Qin, Fangjun Wang, et al. Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides, Chem. Commun., 2012, 48, 961–963. Hongqiang Qin, Fangjun Wang, et al. Isobaric cross- sequence labeling of peptides by using site-selective N-terminus dimethylation. Chem. Commun., 2012, 48, 6265-6267. Hongqiang Qin, Peng Gao, et al. Highly Efficient Extraction of Serum Peptides by Ordered Mesoporous Carbon, Angew. Chem. Inter. Edit., 2011, 50, 12218 –12221. Hongqiang Qin, Liang Zhao, Size-Selective Enrichment of N-Linked Glycans Using Highly Ordered Mesoporous Carbon Material and Detection by MALDI-TOF MS, Anal. Chem, 2011, 83, 7721–7728.

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