崔建国 - 南宁师范大学 - 化学与材料学院

研究领域

具有抗肿瘤活性天然产物的合成、结构改造，新型抗肿瘤药物的设计、合成及生理活性研究，以及有机化学反应中的立体选择性反应研究。

近期论文

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Yanmin HUANG, Jianguo CUI, Sijing Chen, Chunfang GAN, Qiucui YAO, Qifu Lin. Synthesis and Antiproliferative activity of C-Homo-Lactam Derivatives of 7-Deoxycholic Acid, Bioorg. Med. Chem. Lett., 2013, 2265-2267. Yanmin Huang, Jianguo Cui, Ying Li, Lei Fan, Yanxiao Jiao, Shaoyang Su, Syntheses and antiproliferative activity of some sulfated Hydroximinosterols, Med. Chem. Res. 2013, 22 (1): 409–414. DOI 10.1007/s00044-012-0047-5. Chunfang Gan, Jianguo Cui, Yanmin Huang, Linyi Jia, Wanxin Wei, Synthesis and antiproliferative activity of some steroidal lactone compounds. Steroids 2012, 77: 255–259 黄燕敏，崔建国，甘春芳，姚秋翠，贾琳怡，具有生理活性的甾体酰胺类化合物，化学进展，2012， 24（1）：61-69 Yanmin Huang, Jianguo Cui, Qiaoxia Zeng, Chun Zeng, Quan Chen, Aimin Zhou. 6-hydroximino-4-aza-A-homo-cholest-3-one and related analogue as a potent inducer of apoptosis in cancer cells. Steroids 2012, 77: 829–834. Chunfang Gan, Lianghua Fan, Jianguo Cui, Yanmin Huang, Yanxiao Jiao, Wanxin Wei, Synthesis and in vitro antiproliferative evaluation of some ring B abeo-sterols, Steroids 2012, 77: 1061-1068. 林启福，崔建国，甘春芳，刘亮，姚秋翠，黄燕敏，海洋生物中具有生理活性的多羟基甾醇，有机化学，2012,32,2214-2222. Yanmin HUANG, Jianguo CUI, Sijing CHEN, Chunfang GAN, Aimin ZHOU, Synthesis and antiproliferative activity of some steroidal lactams. Steroids 76 (2011) 1346–1350 Yanmin HUANG, Jianguo CUI，Zhengguo ZHONG, Chunfang GAN, Wenyan ZHANG, Huacan SONG, Synthesis and Cytotoxicity of 17a-Aza-D-homo-androster-17-one derivatives, Bioorg. Med. Chem. Lett. 2011, 21：3641–3643 Yanmin Huang, Sijing Chen, Jianguo Cui, Chunfang Gan, Zhiping Liu, Yingliang Wei, Huachan Song. Synthesis and cytotoxicity of A-homo-lactam derivatives of cholic acid and 7-deoxycholic acid. Steroids 2011, 76: 690–694 陈思静、崔建国、李莹、范良华，具有生理活性甾体腙类化合物的研究进展，有机化学，2011, 31(2), 187-192 黄燕敏，李莹，崔建国，王辉，范良华，6-羟基-3-硫酸酯钠甾体化合物的合成及生理活性研究，有机化学，2010，30（11）：1689-1694 张晓佳、崔建国、李莹、陈思静，具有生理活性甾体肟类化合物的研究进展，有机化学, 2010, 30(5), 655-661 Jianguo Cui, Lei Fan, Yanmin Huang, Yi Xin, Aimin Zhou, “Synthesis and evaluation of some steroidal oximes as cytotoxic agents: Structure/Activity Studies (II)”, Steroids. 2009, 74(12), 989-995 Jianguo Cui, Hui Wang, Yanmin Huang, Yi Xin, Aimin Zhou, “Synthesis and cytotoxic analysis of some disodium 3β,6β-dihydroxysterol disulfates”, Steroids. 2009, 74 (13-14) , 1057–1060 崔建国，黄立梁，黄燕敏，范建春，“一种具有抗肿瘤活性胆酸衍生物的合成新方法”，有机化学，2009, 29(6), 971-974 Jian-Guo Cui, Lei Fan, Li-Liang Huang, Hong-Li Liu, Ai-Min Zhou. Synthesis and evaluation of some steroidal oximes as cytotoxic agents: Structure/activity studies (I). Steroids，2009, 74(1), 62-72 崔建国，钟益宁，甘春芳，黄初升，“左旋多巴Schiff碱的合成及其不对称相转移催化烷基化”，有机化学，2008，28（1），78-83 Jianguo Cui, Liliang Huang, Lei Fan, Aimin Zhou，“A facile and efficient synthesis of some (6E)-hydroximino-4-en-3-one steroids, steroidal oximes from Cinachyrella spp. Sponges”，steroids，2008，73 (3)，252–256 崔建国，曾陇梅，苏镜娱，“多羰基甾酮的选择性还原反应研究”，高等学校化学学报，2003，24（4），639 韩莉妲、崔建国、黄初升，“海洋生物中具有生物活性的多羟基甾醇及甾体皂甙”，有机化学，2003，23（3），305-311 Cui Jianguo, Zeng Longmei, Su Jingyu, Lin Cuiwu, “ Regio- and Stereo-selective Reductions of Steroidal 4-en-3,6-dione ”, Chem. Res. Chinese Uni., 2002, 18(4), 400 崔建国、林翠悟、曾陇梅、苏镜娱，“Synthesis of polyhydroxysterols (III): synthesis and structural elucidation of 24-methylenecholest-4-en-3β,6α-diol ”，Steroids, 2002，67（13-14），1015-1019 崔建国、曾陇梅、苏镜娱、何小玉，“24-亚甲基胆甾-4-烯-3β，6α-二醇的结构表征”，有机化学，2002，22（7），515 Cui Jianguo, Zeng Longmei, Su Jingyu, “Synthesis of Polyhydroxysterols (Ⅰ) : Synthesis of 24-methylenecholest-4-en-3β,6β-diol, a cytotoxic natural hydroxylated sterol ”，Steroids, 2001，66（1），33-38 Zeng Longmei, Cui Jianguo, Su Jingyu, “Synthesis of Hydroxylated Sterols(II): Synthesis of 24-methylenecholest-4-en-3β,6α-diol”, Chemical Research in Chinese University, 2000, 16(3 )，271-272 崔建国，曾陇梅，苏镜娱，“多羟基甾醇的合成及抗肿瘤细胞活性构效关系研究”，高等学校化学学报，2000，21（9），1399-1404