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个人简介

2016年6月毕业于华东师范大学有机化学专业,获理学博士学位。

研究领域

(1)有机膦化学 (2)导向具有生物活性有机膦化合物构建方法学研究

发展以绿色合成导向的有机磷化合物构建方法学及其在药物分子合成中的应用研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

[1] L. Chen*, Y.-X. Zou, Recent Progress In the Synthesis of Phosphorus-containing Indole Derivatives, Org. Biomol. Chem. 2018, DOI: 10.1039/C8OB02100G. [2] L. Chen*, Y.-X. Zou, X.-Y. Fang, J. Wu, X.-H. Sun, Brønsted Acid-Catalysed Regiodivergent Phosphorylation of 2-Indolylmethanols to Synthesize Benzylic Site or C3-Phosphorylated Indole Derivatives, Org. Biomol. Chem. 2018, DOI: 10.1039/C8OB02033G. [3] L. Chen*, X.-Y. Fang, Y.-X. Zou, A Highly Efficient Nucleophilic Substitution Reaction Between R2P(O)H and Triarylmethanols to Synthesize Phosphorus-Substituted Triarylmethanes, Org. Biomol. Chem. 2018, 16 (6), 951-956. [4] L. Chen*, Recent Advances in the Catalytic Asymmetric Construction of Phosphorus-Substituted Quaternary Carbon Stereocenters, Synthesis 2018, 50 (3), 440-469. [5] L. Chen,* Y.-X. Zou, X.-Y. Fang, X. Yin, Convenient Synthesis of a-Diarylmethylphosphonates by HOTf Catalyzed Friedel-Crafts Arylation of a-Aryl a-hydroxyphosphonates, Phosphorus, Sulfur Silicon Relat.Elem. 2018, 19 (3), 168-177. [6] L. Chen, Y. Du, X.-P. Zeng, T.-D. Shi, F. Zhou, J. Zhou* Successively Recycle Waste as Catalyst: A One-Pot Wittig/1,4-Reduction/Paal-Knorr Sequence for Modular Synthesis of Substituted Furans,Org. Lett. 2015, 17, 1557-1560. (Highlighted by Organic Chemistry Portal,www.organic-chemistry.org/abstracts/lit4/873.shtm) [7] L. Chen, X.-P. Yin, C.-H. Wang, Jian Zhou* Catalytic Functionalization of Tertiary Alcohols to Fully Substituted Carbon Centres,Org. Biomol. Chem. 2014, 12, 6033-6048. [8] L. Chen, F. Zhu, C.-H. Wang*, Jian Zhou* A Highly Efficient Thiourea Catalyzed Dehydrative Nucleophilic Substitution Reaction of 3-Substituted Oxindoles with Xanthydrols RSC Adv. 2013, 3, 19880-19884. [9] L. Chen, T.-D. Shi, J. Zhou* Waste as Catalyst: Tandem Wittig/Conjugate Reduction Sequence to α-CF3 γ-Keto Esters That Uses Ph3PO as Catalyst for the Chemoselective Conjugate Reduction Chem. Asian. J. 2013, 8, 556-559. (Highlighted by Synfacts 2013‚ 9‚ 559.) [10] L. Chen, J. Zhou* A Highly Efficient Friedel-Crafts Reaction of Tertiary a-Hydroxyesters or a-Hydroxyketones to a-Quternary Esters or Ketones Chem. Asian J. 2012, 7, 2510-2515. (VIP paper, Highlighted by ChemViews Magzine, http://www.chemistryviews.org/details/ezine/2656621/Catalytic Friedel Crafts for Quaternary Carbonyl Compounds.html) [11] L. Chen, F. Zhou, T.-D. Shi, J. Zhou* Metal-free Tandem Friedel-Crafts/Lactonization Reaction to Benzofuranones Bearing a Quternary Center at C3 Position J. Org. Chem. 2012, 77, 4354-4362. (Highlighted by Organic Chemistry Portal, www.organic-chemistry.org/abstracts/lit3/623.shtm) [12] L. Chen*, Acrolein Synlett. 2013, 24, 2775-2776. [13] X.-P. Zeng, Z.-Y. Cao, X. Wang, L. Chen, F. Zhou, C.-H. Wang, J. Zhou* Activation of Chiral (Salen)AlCl Complex by Phosphorane for Highly Enantioselective Cyanosilylation of Ketones and Enones J. Am. Chem. Soc. 2016, 138(1), 416-425. [14] Y.-L. Liu, X. Wang, Y.-L. Zhao, F. Zhu, X.-P. Zeng, L. Chen, C.-H. Wang, X.-L. Zhao, J. Zhou* One-Pot Tandem Approach to Spirocyclic Oxindoles Featuring Adjacent Spiro-Stereocenters Angew. Chem. Int. Ed. 2013‚ 52(51)‚13735-13739. [15] Y.-L. Liu‚ B.-L. Wang‚ J.-J. Cao‚ L. Chen‚ Y.-X. Zhang‚ C.Wang, J. Zhou* Organocatalytic Asymmetric Synthesis of Substituted 3-Hydroxy-2-oxindoles via Morita-Baylis-Hillman Reaction. J. Am. Chem. Soc. 2010‚ 132(43)‚ 15176-15178. [16] Long Chen, Yun-Lin Liu, Jian Zhou (2014): Asymmetric Cooperative Catalysis. In: Multicatalyst System In Asymmetric Catalysis, Eds, Jian Zhou, John Wiley & Sons, New York, Chapter 4, pp 291-372. [17] Long Chen, Zhong-Yan Cao, Jian Zhou (2014): Asymmetric Double Activation Catalysis by Muliticatalyst System. In: Multicatalyst System In Asymmetric Catalysis, Eds, Jian Zhou, John Wiley & Sons, New York, Chapter 5, pp 373-410.

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