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药物及中间体绿色合成技术开发及杂环化合物的合成新方法研究

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•Li, Zhenhua; Wu, Danli; Zhong, Weihui*. Facile and efficient cyclization of anthranilonitrile to 2,4-dichloroquinazoline by bis(trichloromethyl) carbonate and catalytic amount of triphenylphosphine oxide, Heterocycles, 85(6), 1417-1426, 2012. •Yu, Jingbo; Li, Zhenhua; Su, Weike*. Synthesis of quinolines by N-deformylation and aromatization via solvent-free, high-speed ball milling, Synth. Commun., 43(3), 361-374, 2013. •Li, Zhenhua; Xu, Lingmin; Su, Weike*. Synthesis of 2,4-diarylquinolines: nickel-catalysed ligand-free cross-couplings of 4-chloro-2-arylquinolines with arylmagnesium halides in 2-methyltetrahydrofuran,J. Chem. Res., 4, 240-242, 2011. •Su, Weike*; Yu, Jingbo; Li, Zhenhua; Jiang, Zhijiang. Solvent-free cross-dehydrogenative coupling reactions under high speed ball-milling conditions applied to the synthesis of functionalized tetrahydroisoquinolines, J. Org. Chem., 76(21), 9144-9150, 2011. •Su, Weike*; Yu, Jingbo; Li, Zhenhua; Zheng, Bei. Unexpected and divergent reactions of N-formyl-1,2-dihydroquinolines with sodium azide: highly chemoselective formation of 2-substituted quinolines and isoxazolo[4,3-c]quinolines, Synlett, (20), 1281-1284, 2010. •Zhu, Xingyi; Li, Zhenhua; Jin, Can; Xu, Li; Wu, Qianqian; Su, Weike*. Mechanically activated synthesis of 1,3,5-triaryl-2-pyrazolines by high speed ball milling. Green Chem., 11, 163-165, 2009. •Zhu, Xingyi; Li, Zhenhua; Shu, Qiangfeng; Zhou, Chenfeng; Su, Weike*. Mechanically activated solid-state synthesis of flavones by high-speed ball milling. Synth. Commun., 39, 4199-4211, 2009.

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