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药物设计与合成、计算化学、蛋白质化学

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1.Liu X.H. et al. Synthesis, structure, and biological activity of novel (oxdi/tri)azoles derivatives containing 1,2,3-thiadiazole or methyl moiety, Molecular Diversity, 2012, 16(2): 251-260. 2.Liu X.H. et al. Design, Synthesis, Biological Activities, and 3D-QSAR of New N,N'-Diacylhydrazines Containing 2-(2,4-dichlorophenoxy) propane Moiety, Chemical Biology & Drug Design, 2011, 78(4): 689-694. 3.Liu X.H. et al. Synthesis, crystal structure, bioactivity and DFT calculation of new oxime ester derivatives containing cyclopropane moiety, Pesticide Biochemistry & Physiology, 2011, 101(3): 143-147. 4.Liu X.H. et al. High Throughput Receptor Based Virtual Screening Under ZINC-Database, Synthesis and Biological Evaluation of Inhibitors of Ketol-Acid Reductoisomerase, Chemical Biology & Drug Design, 2010, 74(2):228-232. 5.Liu X.H. et al. Synthesis, antifungal activities and 3D-QSAR study of N-(5-substituted-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamides, European Journal of Medicinal Chemistry, 2009, 44(7):2782-2786. 6.Liu X.H. et al. Synthesis of Some N, N'-Diacylhydrazine Derivatives with Radical-Scavenging and Antifungal Activity, Chemical Biology & Drug Design, 2009, 73(3):320-327. 7.Liu X.H. et al. Synthesis, Bioactivity and SAR study of N'-(5-substituted-1,3,4- thiadiazol-2-yl)-N-cyclopropylformyl-thioureas as ketol-acid reductoisomerase Inhibitors, Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, 73(3):320-327. 8.Liu X.H. et al. Synthesis, bioactivity, theoretical and molecular docking study of 1-cyano-N-substituted-cyclopropanecarboxamide as ketol-acid reductoisomerase inhibitor, Bioorganic & Medicinal Chemistry Letters, 2007, 17(13):3784-3788.

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