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[1]Wang S,Gao M,An T,Liu Y,Jin J,Wang G,Jiang C,Tu Y,Hu S,Li J,Wang J,Zhou D*,Cai X*.Genetic diversity and virulence of novel sequence types of Streptococcus suis from diseased and healthy pigs in China.Front Microbiol.2015;6:173.
[2]Wang G,Yu Y,Tu Y,Tong J,Liu Y,Zhang C,Chang Y,Wang S,Jiang C,Zhou EM*,Cai X*.Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Infection Induced Apoptosis and Autophagy in Thymi of Infected Piglets.PLoS One.2015;10:e0128292.
[3]Wang G,Yu Y,Tu Y,Li Y,Tong J,Zhang C,Liu Y,Li A,Jiang C,Wang S,Tao Y,Cai X*.Characterizing the thymic lesions in piglets infected with attenuated strains of highly pathogenic porcine reproductive and respiratory syndrome virus.Vet Immunol Immunopathol.2015.168:258-61.
[4]Jiang C,An T,Wang S,Wang G,Si W,Tu Y,Liu Y,Wu J,Liu S*,Cai X*.Role of the ehxA gene from Escherichia coli serotype O82 in hemolysis,biofilm formation,and in vivo virulence.Can J Microbiol.2015;61:335-41.
[5]Li Z,Wang G,Wang Y,Zhang C,Huang B,Li Q,Li L,Xue B,Ding P,Cai X*,Wang C*,Zhou EM*.Immune responses of pigs immunized with a recombinant porcine reproductive and respiratory syndrome virus expressing porcine GM-CSF.Vet Immunol Immunopathol.2015;168:40-8.
[6]Yu Y,Wang G,Li Q,Du Y,Du T,Mu Y,Xiao S,Zhao Q,Wang C,Sun Y,Xu X,Zhang G,Hsu WH,Cai X*,Zhou EM*.Single-chain anti-idiotypic antibody retains its specificity to porcine reproductive and respiratory syndrome virus GP5.Immunol Lett.2015;163:8-13.
[7]Tu YB#*,Wang G#,Wang YQ,Chen WY,Zhang L,Liu YG,Jiang CG,Wang SJ,Bu ZG,Cai XH*.Extracellular expression and antiviral activity of a bovine interferon-alpha through codon optimization in Pichia pastoris.Microbiol Res.2016,191:12-18.
[8]Wang G#,Yu Y#,Zhang C#,Tu YB,Tong J,Liu YG,Chang YF,Jiang CG,Wang SJ,Zhou E-M*,Cai XH*.Immune responses to modified live virus vaccines developed from classical or highly pathogenic PRRSV following challenge with a highly pathogenic PRRSV strain.Dev Comp Immunol.2016,62:1-7.doi:10.1016/j.dci.2016.04.019.
[9]Dong JG#,Wang G#,Liu YG,Shi WD,Wu JN,Wen HQ,Wang SJ,Tian ZJ,Cai XH*.Quantitative estimation of the replication kinetics of genotype 2 PRRSV strains with different levels of virulence in vitro.J Virol Methods.2016,234:87-9.
[10]Wang G#,Li L#,Yu Y,Tu YB,Tong J,Zhang C,Liu YG,Li YM,Han ZF,Jiang CG,Wang SJ,Zhou E-M,He XJ*,Cai XH*.Highly pathogenic porcine reproductive and respiratory syndrome virus infection and induction of apoptosis in bone marrow cells of infected piglets.J Gen Virol.2016,97:1356-1361.
[11]Tang YD,Liu JT,Wang TY,An TQ,Sun MX,Wang SJ,Fang QQ,Hou LL,Tian ZJ,Cai XH.Live attenuated pseudorabies virus developed using the CRISPR/Cas9 system.Virus Res 2016,225:33-39.
[12]Tang YD#,Fang QQ#,Liu JT,Wang TY,Wang Y,Tao Y,Liu YG*,Cai XH*.Open reading frames 1a and 1b of the porcine reproductive and respiratory syndrome virus(PRRSV)collaboratively initiate viral minus-strand RNA synthesis.Biochem Biophys Res Commun.2016,doi:10.1016/j.bbrc.2016.06.161
[13]Tang YD#,Liu JT#,Fang QQ#,Wang TY#,Sun MX,An TQ,Tian ZJ,Cai XH*.(2016b).Recombinant Pseudorabies Virus(PRV)Expressing Firefly Luciferase Effectively Screened for CRISPR/Cas9 Single Guide RNAs and Antiviral Compounds.Viruses.2016,8(4).
[14]Mingxia Sun,Linlin Hou,Yan-dong Tang,Yonggang Liu,Shujie Wang,Jingfei Wang,Nan Shen,Tongqing An,Zhijun Tian&Xuehui Cai,Pseudorabies virus infection inhibits autophagy in permissive cells in vitro,Sci Rep.2017 Jan 6;7:39964
[15]Yan-Dong Tang,Ji-Ting Liu,Tong-Yun Wang,Ming-Xia Sun,Zhi-Jun Tian,Xue-Hui Cai*Comparison of Pathogenicity-Related Genes in the Current Pseudorabies Virus Outbreak in China.2017,Sci Rep.2017 Aug 10;7(1):7783.doi:10.1038/s41598-017-08269-3.
[16]Zhang HL,Zhang WL,Xiang LR,Leng CL,Tian ZJ,Tang YD,Cai XH.2018.Emergence of novel porcine reproductive and respiratory syndrome viruses(ORF5 RFLP 1-7-4 viruses)in China.Vet Microbiol 222:105-108.
[17]Zhang HL,Tang YD,Liu CX,Xiang LR,Zhang WL,Leng CL,Wang Q,An TQ,Peng JM,Tian ZJ,Cai XH.2018.Adaptions of field PRRSVs in Marc-145 cells were determined by variations in the minor envelope proteins GP2a-GP3.Vet Microbiol 222:46-54.
[18]Tang YD,Guo JC,Wang TY,Zhao K,Liu JT,Gao JC,Tian ZJ,An TQ,Cai XH.2018.CRISPR/Cas9-mediated 2-sgRNA cleavage facilitates pseudorabies virus editing.FASEB J 32:4293-4301.
[19]Wang HM,Liu TX,Wang TY,Wang G,Liu YG,Liu SG,Tang YD,Cai XH.2018.Isobavachalcone inhibits post-entry stages of the porcine reproductive and respiratory syndrome virus life cycle.Arch Virol 163:1263-1270.
[20]Wang TY,Liu YG,Li L,Wang G,Wang HM,Zhang HL,Zhao SF,Gao JC,An TQ,Tian ZJ,Tang YD,Cai XH.2018.Porcine alveolar macrophage CD163 abundance is a pivotal switch for porcine reproductive and respiratory syndrome virus infection.Oncotarget 9:12174-12185.
[21]Wang TY,Fang QQ,Cong F,Liu YG,Wang HM,Zhang HL,Tian ZJ,Tang YD,Cai XH.2019.The Nsp12-coding region of type
[22]PRRSV is required for viral subgenomic mRNA synthesis.Emerg Microbes Infect 8:1501-1510.
[23]Wang TY,Yang YL,Feng C,Sun MX,Peng JM,Tian ZJ,Tang YD,Cai XH.2020.Pseudorabies Virus UL24 Abrogates Tumor Necrosis Factor Alpha-Induced NF-kappaB Activation by Degrading P65.Viruses 12.
[24]Wang SJ,Lyc C,Duan GX,Meng FD,Yang YB,Yu Y,He XJ,Wang ZZ,Gottschalk M,Li GW,Cai XH*,Wang G*.Streptococcus suis Serotype 2 Infection Causes Host Immunomodulation Through Induction of Thymic Atrophy.Infect Immun.2020.Accept.
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