傅磊 - 上海交通大学

研究领域

化学新药的设计、合成及其抗肿瘤、糖尿病、心血管疾病和病毒等方面的临床前期研究；药物剂型研究；化学药物的靶向输送及新型治疗方法的研究和开发；综合医学新系统方法探索；对人体休眠可能性及其机理的研究。

近期论文

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Liu, JB; Jiang, FQ; Jin, Y; Zhang, Y; Liu, JJ Liu, WL; Fu, L; Design, synthesis, and evaluation of 2-substituted ethenesulfonic acid ester derivatives as protein tyrosine phosphatase 1B inhibitors European Journal of Medicinal Chemistry 2012, 57:10-20 Liu, JB; Jiang, FQ; Jiang, XZ; Zhang, W; Liu, JJ; Liu, WL; Fu, L; Synthesis and antimicrobial evaluation of 3-methanone-6-substituted-benzofuran derivatives European Journal of Medicinal Chemistry, 2012, 54,879-886 Ma, FF; Xie, XM; Zhang, L; Peng, ZY; Ding, LN; Fu, L and Zhang, ZG; Palladium-Catalyzed Amidation of Aryl Halides Using 2-Dialkylphosphino-2′-alkoxyl-1,1′-binaphthyl as Ligands. The Journal of Organic Chemistry, 2012,77(12):5279-5285 Zhang, W; Liu, WL; Jiang, XZ; Jiang, FQ; Fu, L; One-pot synthesis of hydroxybenzo[d]oxazole-2-aliphatic acid deribatives by the Meerwein’s reagent. Synthetic Communication, 2012, 42: 2772-2779 Liu, JJ; Cheng, XH; Fu, L; LC-MS based assay method for DPP-IV inhibitor screening and substrate discovery. Analytical Methods, 2012, 4:1797-1805 Zhang, W; Liu, WL; Jiang, XZ; Jiang, FQ; Zhuang, H; Fu, L; Design, synthesis and antimicrobial activity of chiral 2-(substituted-hydroxyl)- 3-(benzo[d]oxazol-5-yl)propanoic acid derivatives. European Journal of Medicinal Chemistry, 2011, 46, 3639 - 3650 Jiang, XZ; Liu, WL; Zhang, W; Jiang, FQ; Fu L; Synthesis and antimicrobial evaluation of new benzofuran derivatives. European Journal of Medicinal Chemistry, 2011, 46, 3526-3530 Liu, WL; Jiang, FQ; Liu, JB; Zhang, JC; Fu, L; Synthesis of bis-ANS fluorescence probe in ionic liquids. Chinese Chemical Letters, 2009, 20, 645–647 Liu, WL; Zhang, JC; Jiang, FQ; Fu, L; Synthesis and Cytotoxicity Studies of New Cryptophycin Analogues. Arch. Pharm. Chem. Life Sci, 2009, 342, 577 – 583 Chen, Y; Peng, YD; Zhang, JC; Fu, L; Synthesis and biological evaluation of novel selenonucleosides. Nucleosides, Nucleotides and Nucleic Acids, 2008, 27, 1001-1008