雷帆 - 清华大学

个人简介

1997年本科毕业于北京医科大学，专业为药学专业。毕业后在北京中医研究所工作，主要从事中药药理学和中医理论的实验研究工作。2000年-2005年在中国医学科学院药用植物研究所学习，获得生药学博士学位。其后在清华大学生科院杜力军老师实验室做博士后，研究方向为心脑血管药理学和分子药理学。2009年博士后出站后在医学院工作，任助研，主要研究方向为中药的分子药理学。2012年起转入医学院药学实验教学中心，任讲师至今。主要参与本科生教学和管理工作。主持或参加国家自然科学基金、科技部重大专项“重大新药创制”、973计划等科研项目共10余项

研究领域

中药小分子活性成分的分子药理学研究药理学教学理论与实践本科生药理学实验的优化与创新

近期论文

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Jiang Xin, Wang Xinpei, Lei Fan*,Yu Xuan, Xing Dongming, Xie Weidong, Du Lijun. Effect of total tannins of pomegranate leaf on glycolipid absorption in normal and obese mice. Mod Chin Med. 2016,18(4):425 Xin-Pei Wang, Fan Lei, Feng Du, Yu-Shuang Chai, Jing-Fei Jiang, Yu-Gang Wang, Xuan Yu, Xiao-Jin Yan, Dong-Ming Xing, Li-Jun Du*. Protection of gastrointestinal mucosa from acute heavy alcohol consumption: The effect of berberine and its correlation with TLR2, 4/IL1β-TNFα signaling. PLoS ONE, 2015, 10(7): e0134044. Yu X, Lu X, Jiang JF，Wang XP，Xing DM，Lei F*，Du LJ. Effects of pomegranate leaf tannis and ellagic acid on in vitro primary rat adipocyte transformation and lipolytic-related factor expression. World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica. 2015, 17(3): 520 Wang Xinpei, Xing Dongming, Jiang Jingfei, Yu Xuan, Yan Xiaojin , Lei Fan*, Du Lijun. Comparison on pomegranate leaf tennis and ananas coumosus leaf phenols on growth of lactation Mice. World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica. 2015, 17(3): 526 Shuang Zhao, Xin-Pei Wang, Jing-FeiJiang, Yu-Shuang Chai, Yu Tian,Tian-Shi Feng, Yi Ding, Jing Huang, Fan Lei, Dong-Ming Xing, Li-Jun Du*. Transport and metabolism behavior of brazilein during its entrance into neural cells. PLOS ONE, 2014:9(10)：e108000 Yu-Shuang Chai, Zhi-Yi Yuan, Fan Lei, Yu-Gang Wang, Jun Hu, Feng Du, Xi Lu, Jing-Fei Jiang, Dong-Ming Xing, Li-Jun Du*. Inhibition of retinoblastoma mRNA degradation through Poly (A) involved in the neuroprotective effect of berberine against cerebral ischemia. PLOS ONE, 2014:9(3): e90850 Yu-Shuang Chai, Jun Hu, Fan Lei, Yu-Gang Wang, Zhi-Yi Yuan, Xi Lu, Xin-Pei Wang, Feng Du, Dong Zhang, Dong-Ming Xing, Li-Jun Du. Effect of berberine on cell cycle arrest and cell survival during cerebral ischemia and reperfusion and correlations with p53/cyclin D1 and PI3K/Akt. European Journal of Pharmacology 2013, 708, 44-55 Yu-Shuang Chai, Fan Lei, Yu Tian, Zhi-Yi Yuan, Xi Lu, Shuang Zhao, Xin-Pei Wang, Dong-Ming Xing, Li-Jun Du. Comprehensive study of the intestinal absorption of four phenolic compounds after oral administration of Ananas comosus leaf extract in vivo and in vitro. African Journal of Pharmacy and Pharmacology, 2013, 7(26), 1781-1792. Jun Hu, Yushuang Chai, Yugang Wang, Michael M. Kheir, Huiying Li, Zhiyi Yuan, Hongjiao Wan, Dongming Xing, Fan Lei*, Lijun Du*. PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia–reperfusion. European Journal of Pharmacology, 2012,674,132-142. Jun Hu, Long Chen, Fan Lei, Yu Tian, Dong-Ming Xing, Yu-Shuang Chai, Shuang Zhao, Yi Ding, Li-Jun Du. Investigation of quercetin stability in cell culture medium：Role in in vitro experiment. African Journal of Pharmacy and Pharmacology, 2012, 6：1069-1076