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A:荧光传感技术 B:细胞激活与调控技术

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Qingshan Du, Weiping Zhu, Zhenjiang Zhao*, Xuhong Qian, Yufang Xu* Novel Benzo-1, 2,3-thiadiazole-7-carboxylate derivatives as plant activators and the development of their agriculturalapplications, Journal of Agricultural Food Chemistry, 2012, 60, 346-353 Shenyi Zhang, Chunmei Yang, Weiping Zhu, Bubing Zeng, Youjun Yang, Yufang Xu*, Xuhong Qian*,Highly selective, naked-eye and fluorescent “off-on” probe for detection of histidine/histidine-rich protein and its application in living cell imaging, Org. Biomol. Chem.,2012,10,1653-1658 Tanyu Cheng, Tao Wang, Weiping Zhu, Xinlei Chen, Youjun Yang, Yufang Xu*, Xuhong Qian*,Red-emission fluorescent probe sensing cadmium andpyrophosphate selectively in aqueous solution,Org. Lett., 2011, 13, 3656-3659. Shenyi Zhang, Chunmei Yang, Weiqiang Lu, Jin Huang, Weiping Zhu, Honglin Li, Yufang Xu*, Xuhong Qian*, A Highly Selective Space-folded Photo-induced Electron Transfer Fluorescent Probe for Carbonic Anhydrase Isozymes IX and Its Applications for Biological Imaging, Chem. Commun., 2011, 47,8301-8303 Kishore Baathulaa, Yufang Xu, Xuhong Qian, Short and Scalable Synthesis of an Anhydride Precursor of the Environment-sensitive Fluorophore 6-DMN, Nature Protocols, 2011, 6,1990-1997. Weiqiang Lu, Xiaofeng Liu, Xianwen Cao, Mengzhu Xue, Kangdong Liu, Zhenjiang Zhao, Xu Shen,Hualiang Jiang, Yufang Xu, Jin Huang*, and Honglin Li*,SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors to Suppress Cell Migration, J. Med. Chem. 2011, 54 (10), 3564–3574 Zhuo Chen, Xin Wang, Weiping Zhu, Xianwen Cao, Linjiang Tong, Honglin Li, Hua Xie,* Yufang Xu,* Shaoying Tan, Dong Kuan, Jian Ding, Xuhong Qian,* Acenaphtho[1,2-b]pyrrole-BasedSelective Fibroblast Growth Factor Receptors 1 (FGFR1) Inhibitors : Design, Synthesis and Biological Activity, J. Med. Chem. 2011, 54 (11), 3732–3745 Chusen Huang, Qin Yin, Weiping Zhu*, Yi Yang*, Xin Wang, Xuhong Qian, Yufang Xu*, Highly Selective Fluorescent Probe for Vicinal Dithiol-Containing Proteins and In-Situ Imaging in Living Cells, Angew. Chem. Int., 2011, 50(33), 7551-6. Hong Yin, Weiping Zhu, Yufang Xu*, Min Dai, Xuhong Qian*, Yuanli Li, Jianwen Liu, Novel aliphatic N-oxide of naphthalimides as fluorescent markers for hypoxic cells in solid tumor, European Journal of Medicinal Chemistry, 2011, 46 ,3030-3037 Tanyu Cheng, Tao Wang, Weiping Zhu, Yangyang Yang, Bubing Zeng, Yufang Xu* and Xuhong Qian*, Modulating the selectivity of Near Infrared Fluorescent Probes Toward Various Metal Ions by Judicious Choice of Aqueous Buffer Solutions, Chem. Commun., 2011, 47, 3915-3917. Lei Cui, Ye Zhong, Weiping Zhu, Yufang Xu*, Qingshan Du, Xin Wang, Xuhong Qian*, and Yi Xiao, A Novel Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell, Org. Lett., 2011, 13, 928-931. Yangyang Yang, Tanyu Cheng, Weiping Zhu, Yufang Xu,* Xuhong Qian*, Highly Selective and Sensitive Near-infrared Fluorescent Sensors for Cadmium in Aqueous Solution, Org. Lett., 2011, 13, 264-267. Lei Cui, Ye Zhong, Weiping Zhu, Yufang Xu*, Xuhong Qian*, Selective and Sensitive Detection and Quantification of Arylamine N-Acetyltransferase 2 by a Ratiometric Fluorescence Probe, Chem. Commun., 2010, 46, 7121 - 7123 (Highlights in Chemical Biology, Predicting drug response, Harriet Brewerton,27 August 2010) Zhuo Chen, Xin Liang, Huanying Zhang, Hua Xie, Jianwen Liu, Yufang Xu*, Weiping Zhu, Yi Wang, Xin Wang, Shaoying Tan, Dong Kuang, Xuhong Qian,*A New Class of Naphthalimide-based Antitumor Agents that Inhibit Topoisomerase II (Topo II) and Induce Lysosomal Membrane Permeabilization (LMP) and Apoptosis,J. Med. Chem. 2010, 53, 2589–2600 Tanyu Cheng, Yufang Xu,* Shenyi Zhang, Weiping Zhu, Xuhong Qian,* Liping Duan A highly sensitive and selective OFF-ON fluorescent sensor for cadmium in aqueous solution and living cell, J. Am. Chem. Soc., 2008, 130 (48), 16160–1616

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