个人简介

学习经历 2004-2009本科南京农业大学动物药学 2009-2015博士研究生南京农业大学基础兽医学 进修情况 2012-2014美国LouisianaStateUniversityHealthSciencesCent联合培养 工作简历 2018.4-至今扬州大学兽医学院讲师 20152018南京师范大学生命科学学院博士后、讲师

研究领域

兽医药理与毒理 肿瘤药理与细胞信号转导

科研情况 基于AK通路的马度米星调控内质网应激致骨骼肌毒性分子机理硏究，国家自然科学基金青年科学基金项目,2020.01-2022.12，主持

近期论文

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1.xinChen,YumeiZhang,ShanxiangJiang*,ShileHuang*,MaduramicininducesapoptosisthroughROS-PP5-JNKpathwayinskeletalmyoblastcellsandmuscletissue.Toxicology. 2019,424:152239. 2.XinChen,YueLi,MengFeng,XiaoyuHu,HaiZhang,RuijieZhang,XiaoqingDong,ChunxiaoLiu,ZhaoZhang,ShanxiangJiang,ShileHuang*,LongChen*.MaduramicininducescardiacmusclecelldeathbytheROS-dependentPTEN/Akt-Erk1/2signalingpathway.Journalofcellularphysiology.2019,234(7):10904-10976 3.XinChen,QianhanWei,QianqianLu,ZetingZhao,ZhengrongYu,YumeiZhang*.SodiumdehydroacetateinducescoagulationdysfunctionbyinhibitinglivervitaminKepoxidereductasecomplexsubunit1inwistarrats.Researchinveterinaryscience.2019,124:39-405 4.XinChenff,XiaoyuHuff,YueLi,CuilanZhu,xiaoqingDong,RuijieZhang,Jingma.ShileHuang*,LongChen*.ResveratrolinhibitsErk1/2-mediatedadhesionofcancercellsviaactivatingPP2A-PTENsignalingnetwork.Journalofcellularphysiology.2019,234(3):28222836 5.xinChen,ShanxiangJiang,ShileHuang*,Maduxamicin-activatedproteinphosphatase2Aresultsinextracellularsignal-regulatedkinase1/2inhibition,leadingtocytotoxicityinmyocardialH9c2cells.Toxicologyletters.2018,284:96-102. 6.XinChen,LongChen,ShanziangJiang*,ShileHuang*.Maduramicininducesapoptosisandnecrosis,andblocksautophagicfluxinmyocardialH9c2cells.Journalofappliedtoxicology.2018,38(3):366-375 7.XinChen,YingGu,KarnikaSingh,ChaoweiShang,MansourehBarzegar,ShanxiangJiang*,ShileHuang*.Maduramicininhibitsproliferationandinducesapoptosisinmyoblastcells.Plosone.2014,9(12):e115652