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天然产物及其类似物的对映体选择性全合成、全合成导向的有机合成方法学,具潜在生物活性的有机过氧化物的设计、合成、体外裂解及抗疟机制等。

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Wu, Y.-K.*; Gao, Jian “Total Synthesis of (+)-Brefeldin A”, Org. Lett. 2008, 10(8), 1533-1536. Zhen, Z.-B.; Gao, J.; Wu, Y.-K.*, “A Chiron Approach to the Total Synthesis of (+)-Aculeatin D”, J. Org. Chem. 2008, 73(18), 7310-7316 Zhang, B.; Nikolovska-Coleska, Z.; Zhang, Y.; Bai, L.; Qiu, S.; Yang, C.-Y.; Sun, H.; Wang, S.;* Wu, Y.-K.*, ""Design, Synthesis and Evaluation of Tricyclic, Conformationally Constrained Smac Mimetics As Antagonists of IAP Proteins"" , J. Med. Chem. 2008, 51(23), 7352-7355. Jian, Y.-J.; Tang, C.-J.; Wu, Y.-K.* , “Enantioselective Total synthesis of Phomallenic Acid C”, J. Org. Chem. 2007, 72(13), 4851-4855. Wu, Y.-K.*; Sun, Y.-P. “A Synthesis of Nonactin and the Proposed Structure of Trilactone”, Org. Lett. 2006, 8(13), 2831-2834. Wu, Y.-K.*; Yang, Y.-Q. “Synthesis of Antimycin A3b”, J. Org. Chem. 2006, 71(11), 4296-4301. Wu, Y.-K.*; Sun, Y.-P. "" An expeditious enantioselective total synthesis of valilactone"", J. Org. Chem. 2006, 71(15), 5748-5751. Wu, Y.-K.;* Sun, Y.-P. ""Novel Chemoselective Tosylation of the Alcoholic Hydroxyl Group of Syn-alpha,beta-Disubstituted beta-Hydroxy Carboxylic Acids "", Chem. Comm. 2005, (14), 1906-1908. Jin, H.-X.; Liu, H.-H.; Zhang, Q.; Wu, Y.-K.* “On the susceptibility of organic peroxy bonds to hydride reduction”, J. Org. Chem. 2005, 70(11), 4240-4247. Sun, Y.-P.; Wu, Y.-K.* ""An Expeditious Synthesis of Nocardiolactone"" Synlett 2005, (9), 1477-1479. Jin, H.-X.; Liu, H.-H.; Zhang, Q.; Wu, Y.-K.* “On the susceptibility of organic peroxy bonds to hydride reduction”, J. Org. Chem. 2005, 70(11), 4240-4247. Wu, Y.-K. *; Shen, X.; Yang, Y.-Q.; Hu, Q.; Huang, J.-H. ""Enantioselective Total Synthesis of (+)-Brefeldin A and 7-epi-Brefeldin A "", J. Org. Chem. 2004, 69(11), 3857-3865. Wu, Y.-K.; Sun, Y.-P.; Yang, Y.-Q.; Hu, Q.; Zhang, Q. ""Removal of Thiazolidinethione Auxiliaries with Benzyl Alcohol Mediated by DMAP "", J. Org. Chem. 2004, 69(18), 6141-6144. Wu, Y.-K.*; Yang, Y.-Q.; Hu, Q. ""A Facile Access to Chiral 4-Isopropyl-, 4-Benzyl-, and 4-Phenyl-oxazolidine-2-thione "", J. Org. Chem. 2004, 69(11), 3990-3992. Wu, Y.-K*.; Li, L.; Sun, Y.-P. ""Synthesis of a 5-oxo-2-tetrahydrofuranyl derivative of an Evans auxiliary via a novel reaction induced by nucleophiles. "", Synlett 2004, (1), 125-127."

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