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个人简介

北京大学博士、中国科学院博士后、加州州立大学洛杉矶分校访问学者。2003年被聘为中南大学化学化工学院教授,2005年起任分析化学学科博士生导师。现任化学化工学院分析科学系主任,中南大学二级教授,入选中南大学531人才计划第二层次。2005年入选中南大学首批“升华学者计划”特聘教授,2009年度入选教育部“新世纪优秀人才支持计划”。研究方向为生物传感器研发、联用仪器的开发以及重大疾病致病机理研究。

研究领域

研究方向为生物传感器研发、联用仪器的开发以及重大疾病致病机理研究。

1. 纳米生物传感器研制; 2. 联用分析仪器的研发; 3. 重大疾病如癌症以及老年痴呆等致病机理的研究。

近期论文

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[1] Jianxiu Wang, M. Li, Z. Shi, N. Li, Z. Gu, Direct electrochemistry of cytochrome c at a glassy carbon electrode modified with single-wall carbon nanotubes. Anal. Chem. 2002, 74, 1993-1997. [2] Jianxiu Wang, X. Zhu, Q. Tu, Q. Guo, C. S. Zarui, J. Momand, X. Sun, F. Zhou, Capture of p53 by electrodes modified with consensus DNA duplexes and amplified voltammetric detection using ferrocene-capped gold nanoparticle/streptavidin conjugates. Anal. Chem. 2008, 80, 769-774. [3] Y. Wang, X. Zhu, M. Wu, N. Xia, J. Wang, F. Zhou, Simultaneous and label-free determination of wild-type and mutant p53 at a single SPR chip preimmobilized with consensus DNA and monoclonal antibody. Anal. Chem. 2009, 81, 8441-8446. (通讯作者) [4] Y. Long, D. Jiang, X. Zhu, J. Wang, F. Zhou, Trace Hg2+ analysis via quenching of the fluorescence of a CdS-encapsulated DNA nanocomposite. Anal. Chem. 2009, 81, 2652-2657. (通讯作者) [5] N. Xia, L. Liu, M. Harrington, J. Wang, F. Zhou, Regenerable SPR sensors for simultaneous detection of Aβ(1–40) and Aβ(1–42) peptides in cerebrospinal fluids with signal amplification by streptavidin conjugated to an N-terminus-specific antibody. Anal. Chem. 2010, 82, 10151-10157. (通讯作者) [6] Jianxiu Wang, Xinyao Yi, Hailin Tang, Hongxing Han, Minghua Wu, Feimeng Zhou, Direct quantification of microRNA at low pM level in sera of glioma patients using a competitive hybridization followed by amplified voltammetric detection, Anal. Chem. 2012, 84, 6400-6406. (通讯作者) [7] Xinyao Yi, Yuanqiang Hao, Ning Xia, Jianxiu Wang, Monica Quintero, Ding Li, Feimeng Zhou, Sensitive and Continuous Screening of Inhibitors of β‑Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) at Single SPR Chips, Anal. Chem. 2013, 85, 3660-3666. (通讯作者) [8] Shen, Congcong; Xia, Xiaodong; Hu, Shengqiang; Yang, Minghui; Wang, Jianxiu, Silver nanoclusters-based fluorescence assay of protein kinase activity and inhibition, Anal. Chem. 2015, 87, 693-698. (通讯作者) [9] Qiuhua Liu, Xi Zhang, Wennan Zeng, Jianxiu Wang, and Zaichun Zhou, Fine-Tuning of Electronic Structure of Cobalt(II) Ion in Nonplanar Porphyrins and Tracking of a Cross-hybrid Stage: Implications for the Distortion of Natural Tetrapyrrole Macrocycles, J. Phys. Chem. B, 2015, 119, 14102-14110. (通讯作者) [10] Wang, Jingrui; Lu, Zhixuan; Tang, Hailin; Wu, Ling; Wang, Zixiao; Wu, Minghua; Yi, Xinyao; Wang, Jianxiu, Multiplexed Electrochemical Detection of MiRNAs from Sera of Glioma Patients at Different Stages via the Novel Conjugates of Conducting Magnetic Microbeads and Diblock Oligonucleotide-Modified Gold Nanoparticles, Anal. Chem., 2017, 89, 10834-10840. (通讯作者) [11] Hu, Shengqiang; Yi, Tiantian; Huang, Zhicheng; Liu, Biwu; Wang, Jianxiu; Yi, Xinyao; Liu, Juewen, Etching Silver Nanoparticles by Poly-Cytosine DNA, Materials Horizons, 2019, 6, 155-159. (通讯作者) [12] Xinyao Yi, Yonghong Xia, Binrong Ding, Ling Wu, Shengqiang Hu, Zixiao Wang, Jianxiu Wang*, Dual-Channel Surface Plasmon Resonance for Quantification of ApoE Gene and Genotype Discrimination in Unamplified Genomic DNA Extracts. ACS Sensors, 2018, 3, 2402-2407. [13] Xiaodong Xia, Yuanqiang Hao, Shengqiang Hu, Jianxiu Wang, Hairpin DNA probe with 5'-TCC/CCC-3' overhangs for the creation of silver nanoclusters and miRNA assay, Biosensors and Bioelectronics, 2014, 51, 36-39. (通讯作者) [14] Zhixuan Lu, Hailin Tang, Daohong Wu, Yonghong Xia, Minghua Wu, Xinyao Yi, Hengfeng Li, Jianxiu Wang, Amplified voltammetric detection of miRNA from serum samples of glioma patients via combination of conducting magnetic microbeads and ferrocene-capped gold nanoparticle/streptavidin conjugates, Biosensors and Bioelectronics, 2016, 86, 502-507. (通讯作者) [15] Shengqiang Hu, Baoyu Ye, Hailin Tang, Fan Wu, Xinyao Yi, Tiantian Yi, Daohong Wu, Ling Wu, Jianxiu Wang*, Journal of Materials Chemistry B, 2018, 6, 1187-1194.

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