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有机合成和甾体化学 有机合成;药物合成化学;杂环化学;化学生物学;有机合成方法学;精细化工;香精香料。

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Pd(PPh3)4/AgOAc-catalyzed coupling of 17-steroidal triflates and alkynes: Highly efficient synthesis of D-ring unsaturated 17-alkynylsteroids; Qian Sun, Chenggang Jiang, Hangxian Xu, Zonglei Zhang, Lanhai Liu, Cunde Wang* Steroids,2010, Volume 75, Issue 12, Pages 936-943 Chlorotrimethylsilane-promoted one-pot synthesis of steroidal[17,16-d] pyrimidines;Cunde Wang,* Hangxian Xu, Zengyang Xie, Xingbin Wang, Zonglei Zhang, Qian Sun Steroids,2010, Volume 75, Issue 12, Pages 1033-1038. Optimization of the Abnormal Beckmann Rearrangement: Application to Steroid 17-Oximes. Wang, Cunde; Jiang, Xin; Shi, Haijian; Lu, Jun; Hu, Yuefei; Hu, Hongwen. Journal of Organic Chemistry 2003, 68(11), 4579-4581. Preparation of (5α,13α)-D-azasteroids as key precursors of a new family of potential GABAA receptor modulators. Wang Cunde; Wang Shaozhong; Xu Yingju; Hu Yuefei; Hu Hongwen Steroids 2003 68(7-8), 677-683. Novel preparation of non-racemic 1-[α-(1-azacycloalkyl)benzyl]-2-naphthols from Betti base and their application as chiral ligands in the asymmetric addition of diethylzinc to aryl aldehydes. Lu, Jun; Xu, Xuenong; Wang, Shaozhong; Wang, Cunde; Hu, Yuefei; Hu, Hongwen. Journal of the Chemical Society, Perkin Transactions 1 2002, (24), 2900-2903. The rapid synthesis of β-nitrostyrenes under microwave irradiation without solvent. Wang, Cunde; Wang, Song. Synthetic Communications 2002, 32(22), 3481-3486. A novel and efficient conversion of aldehydes to 1,1-diacetates catalyzed with FeCl3/SiO2 under microwave irradiation. Wang, Cunde; Li, Minghua. Synthetic Communications 2002, 32(22), 3469-3473. Synthesis of chiral ligands derived from the Betti base and their use in the enantioselective addition of diethylzinc to aromatic aldehydes. Lu, Jun; Xu, Xuenong; Wang, Cunde; He, Jiangang; Hu, Yuefei; Hu, Hongwen. Tetrahedron Letters 2002, 43(46), 8367-8369. A Practical and Facile Route for the Preparation of 18-Norandrostan-17-ones from Androstan-17-ones Using SmI2-Promoted Cyclization and Dehydroxylation. Jiang, Xin; Wang, Cunde; Hu, Yuefei; Hu, Hongwen; Covey, Douglas F. Journal of Organic Chemistry 2000, 65(11), 3555-3557. Preparation of (S)-(+)- and (R)-(-)-1-(-aminobenzyl)-2-naphthol. Hu, Yuefei; Lu, Jun; Xu, Xuenong; Wang, Cunde; Wang, Shaozhong; Hu, Hongwen. Faming Zhuanli Shenqing Gongkai Shuomingshu 2002, 7 pp. CODEN: CNXXEV CN 1348952 A 20020515 Patent written in Chinese. Application: CN 2001-127170 20010904. CAN 139:69061 AN 2003:557130 CAPLUS Synthesis of thiosemicarbazones under microwave irradiation. Wang, Cun-De; Lu, Jun; Shi, Xin-Zhong; Feng, Yun-Hua. Synthetic Communications 1999, 29(17), 3057-3061. Synthesis of diacetals of 2,2-bis(hydroxymethyl)-1,3-propanediol under microwave irradiation. Wang, Cun-De; Shi, Xin-Zhong; Xie, Ren-Jian. Synthetic Communications 1997, 27(14), 2517-2520. Abnormal Beckmann fragmentation/ring closing metathesis route for preparation of 18-nor-Δ13(17)-androgens and their 18-nor-13,17-epoxide derivatives Wang, Cunde; Rath, Nigam P.; Covey, Douglas F. Tetrahedron Lett. 2006, 47, 7837-7839. Neurosteroid migration to intracellular compartments reduces steroid concentration in the membrane and diminishes GABA-A receptor potentiation Ping Li, Hong-Jin Shu, Cunde Wang, Steven Mennerick, Charles F. Zorumski, Douglas F. Covey, Joe Henry Steinbach1 and Gustav Akk J Physiol 584.3 (2007) pp 789–800 789. Long-lived anticonvulsant and anesthetic effects of a fluorescent neurosteroid analogue activated by visible light Eisenman, Lawrence N.; Shu, Hong-Jin; Akk, Gustav; Wang, Cunde; Manion, Brad D.; Kress, Geraldine; Evers, Alex S.; Stein, Joe Henry; Covey, Douglas F.; Zorumski, Charles F. and Mennerick, Steven Nature Neuroscience (2007) 10, 523 - 530. NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue Lawrence N. Eisenman, Hong-Jin Shu, Cunde Wang, Elias Aizenman, Douglas F. Covey, Charles F. Zorumski and Steven Mennerick J Physiol (2009) 587.12 pp 2937–2947. A rapid synthesis of alkyl -cyanoacetyl glycolates under microwave irradiation in dry medium. Wang, Cunde; Zhang, Hui. Department of Chemistry, Yangzhou University, Yangzhou, Peop. Rep. China. Synthetic Communications (2002), 32(22), 3465-3468. Neurosteroid Access to the GABAA Receptor Akk Gustav, Shu Hong-Jin, Wang Cunde, Steinbach Joe Henry, Zorumski Charles F., Covey Douglas F., Mennerick Steven The Journal of Neurosciene 2005, 25(50), 11605-11613. Microwave-promoted N-alkylation of acridones without solvent. Wang, Cunde; Hang, Tianlong; Zhang, Hui. Synthetic Communications 2003, 33(3), 451-456. Efficient Synthesis of Conjugated Alkynyl Cycloalkenones: Pd(PPh3)4—AgOAc-Catalyzed Direct Coupling of 1-Alkynes with 3-Oxocycloalkenyl Triflates. Chenggang Jiang, Zonglei Zhang, Hangxian Xu, Liang Sun, Lanhai Liu, Cunde Wang* Applied Organometallic Chemistry, 2010,Volume 24, Issue 3, Pages: 208–214,

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