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个人简介

教育经历 2001.09-2004.06, 天津大学, 理学院, 博士研究生 1996.09-1999.06, 青岛化工学院, 化工系, 硕士研究生 1991.09-1995.06, 青岛化工学院, 化工系, 本科 主要职历 2014.07-至今, 华中农业大学信息学院, 教授 、博士生导师 2009.02-2014.06, 华中农业大学生命科学技术学院, 教授 、博士生导师 1999.07-2009.02, 山东理工大学生命科学学院, 历任讲师、副教授 1995.07-1996.08, 山东滨州印染集团公司, 质检员

研究领域

植物及微生物基因组、转录组分析;代谢及蛋白互作网络构建及分析

近期论文

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1.Sun J, Liu H, Liu J, Cheng S, Peng Y, Zhang Q, Yan J, Liu HJ*,Chen LL*.CRISPR-Local: a local single-guide RNA (sgRNA) design tool for non-reference plant genomes.Bioinformatics, bty970,https://doi.org/10.1093/bioinformatics/bty970 2.Song JM, Lei Y, Shu CC, Ding Y, Xing F, Liu H, Wang J, Xie W, Zhang J,Chen LL*. Rice Information GateWay: a comprehensive boinformatics platform for indica rice genomes.Mol Plant, 2018, 11(3):505-507. 3.Liu H, Ding Y, Zhou Y, Jin W, Xie K*,Chen LL*.CRISPR-P 2.0: an improved CRISPR-Cas9 tool for genome editing in plants.Mol Plant, 2017, 10(3):530-532. 4.Zhang J#,Chen LL#, Sun S, et al. Building two indica rice reference genomes with PacBio long-read and Illumina paired-end sequencing data.Sci Data, 2016, 3:160076.#Co-firstauthors. 5.Zhang J#,Chen LL#, Xing F#, et al. Extensive sequence divergence between the reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui 63.ProcNatl Acad Sci U S A, 2016, 113(35): E5163-71.#Co-firstauthors. 6.Ding Y, Li H,Chen LL*, Xie K*. Recent advances in genome editing using CRISPR/Cas9.Front Plant Sci., 2016, 7:703. 7.Guo J, Zhang H, Wang C, Chang JW,Chen LL*. Construction and analysis of a genome-scale metabolic network forBacillus licheniformisWX-02.Res Microbiol., 2016, 167(4): 282-9. 8.Guo J, Cheng G, Gou XY, Xing F, Li S, Han YC, Wang L, Song JM, Shu CC, Chen SW*,Chen LL*. Comprehensive transcriptome and improved genome annotation ofBacillus licheniformisWX-02.FEBS Lett., 2015, 589(18): 2372-81. 9.Wang C, Deng ZL, Xie ZM, Chu XY, Chang JW, Kong DX, Li BJ, Zhang HY,Chen LL*. Construction of a genome-scale metabolic network of the plant pathogenPectobacterium carotovorumprovides new strategies for bactericide discovery.FEBS Lett., 2015, 589(3): 285-94. 10.Chen D, Fu LY, Zhang Z, Li G, Zhang H, Jiang L, Harrison AP, Shanahan HP, Klukas C, Zhang HY, Ruan Y*,Chen LL*, Chen M*. Dissecting the chromatin interactome of microRNA genes.Nucleic Acids Res.,2014, 42(5): 3028-43. 11.Ding YD, Chang JW, Guo J, Chen D, Li S, Xu Q, Deng XX, Cheng YJ,Chen LL*. Prediction and functional analysis of the sweet orange protein-protein interaction network.BMC Plant Biol.,2014, 14(1): 213. 12.Lei Y, Lu L, Liu HY, Li S, Xing F,Chen LL*. CRISPR-P: A Web Tool for Synthetic Single-Guide RNA Design of CRISPR-System in Plants.Mol Plant,2014, 7(9): 1494-1496. 13.Guo FB, Lin Y,Chen LL*. Recognition of protein-coding genes based on Z-curve algorithms.Current Genomics, 2014, 15:95-103. 14.Xu Q#,Chen LL#, Ruan X#, et al. The draft genome of sweet orange (Citrus sinensis).Nature Genetics, 2013, 45: 59-66.#Co-firstauthors. 15.Jiao WB, Huang D, Xing F, HuY, Deng XX, Xu Q*,Chen LL*. Genome-wide characterization and expression analysis of genetic variants in sweet orange.Plant J., 2013, 75: 954-964. 16.Chen D, Yuan C, Zhang J, Zhang Z, Bai L, Meng Y,Chen LL*, Chen M*. PlantNATsDB: a comprehensive database of plant natural antisense transcripts.Nucleic Acids Res., 2012, 40: D1187-1193.

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