代荣阳 - 西南医科大学

个人简介

博士，教授，硕士生导师，澳门科技大学兼职博导。2001年于泸州医学院获临床医学学士学位，2006年于泸州医学院获理学硕士学位，2009年于上海交通大学医学院获肿瘤学博士学位。2010年8月至2012年11月在中国人民解放军第二军医大学东方肝胆外科医院从事博士后研究。2013年11月至2014年11月在哈佛医学院访问研究。

研究领域

目前主要从事肝脏疾病研究，应激与肝癌关系是该团队的主要研究方向。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1]Feng C, He K, Zhang C, Su S, Li B, Li Y, Duan CY, Chen S, Chen R, Liu Y, Li H, Wei M, Xia X, Dai R* (代荣阳). JNK Contributes to the Tumorigenic Potential of Human Cholangiocarcinoma Cells through the mTOR Pathway Regulated GRP78 Induction. PLoS One. 2014;9(2):e90388. (IF: 3.73) [2]RY Dai(代荣阳), XF Zhao, JJ Li, R Chen, ZL Luo, LX Yu, SK Chen, CY Zhang, CY Duan, YP Liu, CH Feng, XM Xia, H Li, J Fu, HY Wang*(王红阳). Implication of transcriptional repression in compound C-induced apoptosis in cancer cells.Cell Death Dis. 2013;4:e883. (IF: 6.044) [3]Chen R, Duan CY, Chen SK, Zhang CY, He T, Li H, Liu YP, Dai RY*(代荣阳). The suppressive role of p38 MAPK in cellular vacuole formation. J Cell Biochem. 2013;114:1789-99. (IF: 3.062) [4]Chen R, Li J, Feng C, Chen S, Liu Y, Duan C, Li H, Xia X, He T, Wei M, Dai R*(代荣阳). c-Met function requires N-linked glycosylation modification of pro-Met. J Cell Biochem. 2013;114(4):816-22. (IF:3.062, 引用次数:1) [5]Dai R(代荣阳), Li J, Fu J, Chen Y, Wang R, Zhao X, Luo T, Zhu J, Ren Y, Cao J, Qian Y, Li N, Wang H*(王红阳). The Tyrosine Kinase c-Met Contributes to the Pro-tumorigenic Function of the p38 Kinase in Human Bile Duct Cholangiocarcinoma Cells. J Biol Chem. 2012;287(47):39812-23. (IF:4.651, 引用次数:5) [6]Dai R(代荣阳), Li J, Fu J, Chen Y, Yu L, Zhao X, Qian Y, Zhang H, Chen H, Ren Y, Su B, Luo T, Zhu J, Wang H*(王红阳). Disturbance of Ca2+ homeostasis converts pro-Met into non-canonical tyrosine kinase p190MetNC in response to endoplasmic reticulum stress in MHCC97 cells. J Biol Chem. 2012;287(18):14586-97. (IF:4.651, 引用次数:7 ) [7]Dai R(代荣阳), Yan D, Li J, Chen S, Liu Y, Chen R, Duan C, Wei M, Li H*(李洪), He T. Activation of PKR/eIF2α signaling cascade is associated with dihydrotestosterone-induced cell cycle arrest and apoptosis in human liver cells. J Cell Biochem. 2012;113(5):1800-8. (IF:3.062, 引用次数:8) [8]Run Chen, Rongyang Dai(代荣阳)+, Chunyan Duan, Youping Liu, Shaokun Chen, Dongmei Yan, Chuanning Chen, Mei Wei, Hong Li*(李洪). Unfolded Protein Response Suppresses Cisplatin-induced Apoptosis via Autophagy Regulation in Human Hepatocellular Carcinoma Cells. Folia Biol (Praha). 2011;57(3):87-95. (并列第一作者, IF:1.101, 引用次数:18) [9]Liu Y, Liu P, Dai R(代荣阳) +, Wang J, Zheng Y, Shen J, Guo F, Wang L, Li H, Wei M*(魏嵋). Analysis of plasma proteome from cases of the different traditional Chinese medicine syndromes in patients with chronic hepatitis B. J Pharm Biomed Anal. 2012;59:173-8. (并列第一作者, IF:2.967, 引用次数:11) [10]Rongyang Dai(代荣阳), Juan Li, Youping Liu, Dongmei Yan, Shaokun Chen, Chunyan Duan, Xiaoyan Liu, Tao He, Hong Li*(李洪). MiR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27Kip1- and MEK/ERK-mediated cell cycle regulation. Biol Chem. 2010;391(7):791-801. (IF:2.683, 引用次数:27) [11]Rongyang Dai(代荣阳), Shaokun Chen, Dongmei Yan, Run Chen, Youping Liu, Chunyan Duan, Juan Li, Tao He, Hong Li*(李洪). PI3K/Akt promotes GRP78 accumulation and inhibits endoplasmic reticulum stress-induced apoptosis in HEK293 cells. Folia Biol(PRAHA). 2010;56(2):37-46. (IF:1.101, 引用次数:14) [12]Rong-Yang Dai(代荣阳), Yao Chen, Jing Fu, Li-Wei Dong, Yi-Bin Ren, Guang-Zhen Yang, You-Wen Qian, Jie Cao, Shan-Hua Tang, Sheng-Li Yang and Hong-Yang Wang*(王红阳). p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity. Cell Res. 2009;19(11):1243-57. (IF:10.526, 引用次数:25) [13]Dai R(代荣阳), Chen R, Li H*(李洪). Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells. Int J Oncol. 2009;34(6):1749-57. (IF:2.657, 引用次数:48) [14]Zhang HL, Yu LX, Yang W, Tang L, Lin Y, Wu H, Zhai B, Tan YX, Shan L, Liu Q, Chen HY, Dai RY(代荣阳), Qiu BJ, He YQ, Wang C, Zheng LY, Li YQ, Wu FQ, Li Z, Yan HX, Wang HY*(王红阳). Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats. J Hepatol. 2012;57(4):803-12. (IF:9.858, 引用次数:7) [15]Cao J, Chen Y, Fu J, Qian YW, Ren YB, Su B, Luo T, Dai RY(代荣阳), Huang L, Yan JJ, Wu MC, Yan YQ, Wang HY*(王红阳). High Expression of Proline-Rich Tyrosine Kinase2 is Associated with Poor Survival of Hepatocellular Carcinoma via Regulating Phosphatidylinositol 3-Kinase/AKT Pathway.Ann Surg Oncol. 2013;20(Suppl 3):S312-23. [Epub ahead of print] (IF:4.12, 引用次数:2) [16]Qian YW, Chen Y, Yang W, Fu J, Cao J, Ren YB, Zhu JJ, Su B, Luo T, Zhao XF, Dai RY(代荣阳), Li JJ, Sun W, Wu MC, Feng GS, Wang HY*(王红阳). p28GANK prevents degradation of Oct4 and promotes expansion of tumor-initiating cells in hepatocarcinogenesis. Gastroenterology. 2012;142(7):1547-58. (IF:12.821, 引用次数:10) [17]Li-wei Dong, Guang-zhen Yang, Yu-fei Pan, Yao Chen, Ye-xiong Tan, Rong-yang Dai(代荣阳), Yi-bin Ren, Jing Fu, Hong-yang Wang*(王红阳). The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling. Cell Res.2011;21(8):1248-61. (IF:10.526, 引用次数:17) [18]冯春红,陈润,陈绍坤,李娟,段春燕,刘友平,李洪,代荣阳*. 真核起始因子2α的磷酸化抑制顺铂介导的肝癌细胞凋亡.中华肝脏病杂志, 2013;21(04):290-4. (Medline收录)