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主要从事有机合成,包括不对称有机合成、手性催化、手性拆分以及化学生物学方面的研究

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Zhi-yong Gong, Chi-yu Wei, Ye Shi, Qing-chuan Zheng, Zhi-guang Song*, Zaiqun Liu, Novel chiral bifunctional l-thiazoline-amide derivatives: design and application in the direct enantioselective aldol reactions, Tetrahedron , 2014, 70(9), 1827–1835 Zhi-hui Liu , De-jun Li, Dan Jiang, Chuan Xiao, Zhi-guang Song* and Ying-hua Jin, Design, Synthesis and Antitumor Activity in vitro of a Series of 3-Arylcoumarins, Chem. Res. Chinese U. 2013, 29 (6): 1125-1128. Chao Sun, Xiao-Xi Guo, Dan Zhu, Chuan Xiao, Xiao Bai, Yang Li, Zhuo Zhan, Xiang-Long Li, Zhi-Guang Song*, and Ying-Hua Jin*, Apoptosis is Induced in Cancer Cells via the Mitochondrial Pathway by the Novel Xylocydine-Derived Compound JRS-15, Int. J. Mol. Sci. 2013, 14, 850-870. Zhi-guang Song, Zhi-yong Gong, Gou-dong. Feng, Facile synthesis of a water-soluble bidentate pyridine-acid ligand and the application in quantifying bovine serum albumin by fluorescence spectroscopy, Analytical Methods, 2012, 4, 899-901. Zhi-Guang Song, Chuan Xiao, Yanna Dai, Qiang Fei, Yanfu Huan and Guodong feng, Fluorescence quenching amplification in silica nanosensors for Au3+, Nanotechnology, 2012, 23, 425501. Chuan Xiao, Xu-Yang Luo, De-Jun Li, Hang Lu, Zai-Qun Liu, Zhi-Guang Song*, Ying-Hua Jin, Synthesis of 4-methylcoumarin derivatives containing 4, 5-dihydropyrazole moiety to scavenge radicals and to protect DNA, Eur. J. Med.Chem. 2012 , 53, 159-167. Zhi-yong Gong, Qing-wen Liu, Peng-chong Xue, Ke-chang Li, Zhi-guang Song*,Zai-qun Liu and Ying-hua Jin, Novel chiral thiazoline-containing N-O ligands in the asymmetric addition of diethylzinc to aldehydes: substituent effect on the enantioselectivity, Applied Organometallic Chemistry, 2012, 26, 121-129. Chuan Xiao, Chao Sun, Wei-wei Han, Feng Pan, Dan Zhu, Yu Li, Zhi-Guang Song*, Ying-Hua Jin*, Synthesis of 6-(het) ary Xylocydine Analogues and Evaluating their Inhibitory Activities of CDK1 and CDK2 inVitro, Bioorganic & Medicinal Chemistry, 2011, 19 (23), 7100-7110 Yang Yang, Zhi-Guang Song, Zai-Qun Liu, Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radials, Free Radical Res., 2011, dio: 10.3109/10715762. 2010. 540576 Chuan Xiao, Zhi-Guang Song, Zai-Qun Liu, Synthesis of methyl-substituted xanthotoxol to clarify prooxidant effect of methyl on radical-induced oxidation of DNA, Eur. J. Med. Chem, 2010, 45, 2559-2566. Jian-nan Zheng, Chuan Xiao, Qiang Fei, Ming Li, Bao-jun Wang, Guo-dong Feng, Hong-mei Yu, Yan-fu Huan* and Zhi-Guang Song*, A highly sensitive and selective fluorescent Cu2+ sensor synthesized with silica nanoparticles, Nanotechnology, 2010, 21, 045501. Jing Li, Yan-Mei Shang, Chuan Xiao, Zhi-Guang Song*, Ye-Zhi and Huan-min Huang, Synthesis and Crystal Structure of (R)-4-Hydroxymethyl-2-thioxo Thiazolidine and Its Asymmetric Catalysis, Chem. Res. Chinese U. 2009, 25 (01): 43-46.

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