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研究领域

主要从事生物化学传感器和中草药有效成分提取、分离和测定方面的研究工作。 1. 生物分析。利用表面等离子体子共振(SPR)生物传感器研究了一些生物分子的测定及生物分子间相互作用,研究的生物分子有B因子、补体4、破伤风抗体、bFGF,心肌肌钙蛋白、DNA等,在Anal. Biochem.,Anal. Chim. Acta.,Talanta等杂志上发表了一系列论文。 2. 生物分子与药物分子相互作用的研究。利用SPR技术、荧光光谱法和吸收光谱法等光谱技术,研究了生物分子与药物分子间的相互作用,研究的药物涉及中药有效成分和西药,在Spectrochim. Acta,J. Mol. Struct.等杂志上发表了一系列论文。 3. 中药有效成分提取方法的研究。在研究常规提取方法的基础上,对微波萃取法进行了较详细的研究,并建立了一些新的微波萃取方法,如谐振腔流动微波萃取法、超声波雾化萃取法、微波无溶剂萃取法等。在高等学校化学学报、分析化学等杂志上发表一系列论文。

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Determination of affinities and antigenic epitopes of bovine cardiac troponin Ⅰ (cTnⅠ)with monoclonal antibodies by surface plasmon resonance biosensor,Analytical Biochemistry,2003,314,301. Corresponding author An optical immunosensor based on surface plasmon resonance for determination of bFGF,Microchemical Journal,2003,74,93. Corresponding author 一种新型微波辅助萃取法用于中药刺五加中总黄酮萃取的研究,高等学校化学学报,2003,24(8),1403. Corresponding author An optical surface plasmon resonance biosensor for determination of tetanus toxin,Talanta,2004,62,773. Corresponding author An acousto-optic tunable filter –based surface plasmon resonance biosensor for determination of human factor B,Analytica Chimica Acta,2004,511,97. Corresponding author Investigation of the interaction between flavonoids and human serum albumin,Journal of Molecular Structure,2004,703,37. Corresponding author Sensitivity-enhancement of wavelength-modulation surface plasmon resonace biosensor for human complement factor 4,Analytical Biochemistry,2004,333,99. Corresponding author Microwave-assisted Extraction of Rutin and Quercetin from Flos Sophorae,Chem. Res. Chinese U,2004,20,703. Corresponding author 微波辅助流动萃取槐花中的黄酮类成分,高等学校化学学报,2004,25,850. Corresponding author 刺五加中黄酮类化合物的微波辅助提取研究,分析化学,2004,32,360. Corresponding author 中草药中槲皮素的毛细管电泳法测定,高等学校化学学报,2005,26(4),657. Corresponding author Molecular spectroscopic study on the interaction of tetracyclines with serum albumins,Spectrochimica Acta Part A,2005,61,629. Corresponding author 微波萃取高效液相色谱法测定口红中芳香胺类化合物,高等学校化学学报,2005,26(9),1623. Corresponding author Acousto-optic tunable filter-surface plasmon resonance immunosensor for fibronectin,Analytica Chimica Acta,2005,551,98. Corresponding author Separation and identification of Aconitum alkaloids and their metabolites in human urine,Toxicon,2005,46(5),500. Corresponding author

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