刘洋 - 沈阳药科大学 - 制药工程学院

个人简介

教育经历 2002.09－2006.12: 沈阳药科大学药物化学专业理学博士 1999.09－2002.07: 湖南大学有机化学专业理学硕士 1995.09－1999.07: 湖南大学化学专业理学学士工作经历 2019.12－今: 沈阳药科大学制药工程学院教授 2014.10－2016.05: 美国克利夫兰州立大学化学系访问学者 2010.12－2019.12: 沈阳药科大学制药工程学院副教授 2007.03－2010.12: 沈阳药科大学制药工程学院讲师

研究领域

药物化学/制药工程/具有糖基结构的活性天然产物的合成及生物活性研究；糖化学及糖基化药物的研究

近期论文

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Zuo-Peng Zhang, Ye Zhong, Zhen-Bin Han, Lin Zhou, Hua-Sheng Su, Jian Wang, Yang Liu*, Mao-Sheng Cheng*. Synthesis, molecular docking analysis and biological evaluations of saccharide-modified thiadiazole sulfonamide derivatives. International Journal of Molecular Sciences, 2021, 22(11): 5482. Zhuang Hou, Chuanchao Li, Yichuang Liu, Miao Zhang, Yitong Wang, Zhanfang Fan, Chun Guo, Bin Lin*, Yang Liu*. Design, synthesis and biological evaluation of carbohydrate-based sulfonamide derivatives as topical antiglaucoma agents through selective inhibition of carbonic anhydrase II. Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35(1): 383–390. Gaofei Wei*, Jiahong Sun, Weijing Luan, Zhuang Hou, Shuai Wang, Shanshan Cui, Maosheng Cheng*, Yang Liu*. Natural product Albiziabioside A conjugated with pyruvate dehydrogenase kinase inhibitor dichloroacetate to induce apoptosis-ferroptosis-M2-TAMs polarization for combined cancer therapy. Journal of Medicinal Chemistry, 2019, 62(19): 8760–8772. Qiaolin Tong, Yang Liu*, Xuezhi Gao, Zhanfang Fan, Tianfu Liu, Bo Li, Dangsheng Su, Qinghe Wang*, Maosheng Cheng*. A deoximation method for deprotection of ketones and aldhydes using a graphene-oxide-based co-catalysts system. Advanced Synthesis & Catalysis, 2019, 361(13): 3137–3145. Hui-ning Li, Yang Liu*, Zuo-peng Zhang, Zhi-peng Wang, Jing-zheng Hao, Feng-ran Li, Zhan-fang Fan, Li-bo Zou, Mao-sheng Cheng. Synthesis, biological evaluation and structure-activity relationship studies of hederacolchiside E and its derivatives as potential anti-Alzheimer agents. European Journal of Medicinal Chemistry, 2018, 143: 376–389.