贺晓鹏 - 华东理工大学 - 化学与分子工程学院

个人简介

Xiao-Peng He (Franck) received his BSc in Applied Chemistry (2006) and PhD in Pharmaceutical Engineering (2011) with Prof. Xiaoxin Shi and Prof. Yi-Tao Long from ECUST. Sponsored by the French Embassy, He completed a co-tutored doctoral program at ENS Cachan (France) from July 2008 to February 2009 under the supervision of Prof. Juan Xie. Then he carried out his postdoctoral research with Prof. Kaixian Chen (SIMM, CAS) at ECUST from 2011 to 2013. He’s now a professor at School of Chemistry and Molecular Engineering, ECUST, where his research interests span chemical glycobiology to fluorescent molecular probes for disease diagnostics and theranostics. Prof. He has co-authored over 100 peer-reviewed papers and is co-inventor of 8 Chinese patents. 工作经验 2018 - 华东理工大学，化学与分子工程学院，费林加诺贝尔奖科学家联合研究中心，教授 2014 - 2018 华东理工大学，化学与分子工程学院，副研究员（2015，2017年分别获硕士和博士生导师资格） 2013 - 2014 华东理工大学，化学与分子工程学院，讲师 2011 - 2013 华东理工大学，化学与分子工程学院，博士后（合作导师：陈凯先院士）学历 2008 - 2009 法国Cachan高等师范学校，联合培养（导师：Prof. Juan Xie） 2006 - 2011 华东理工大学，药学院，硕博连读（导师：施小新教授，龙亿涛教授） 2002 - 2006 华东理工大学，化学与分子工程学院，本科奖励和荣誉 2018 中国化学会青年化学奖 2018 中国化学会化学生物学奖（35周岁以下突出贡献） 2017 国家自然科学基金优秀青年科学基金项目 2016 上海市青年科技启明星计划 2014 华东理工大学青年英才计划 2013 上海市优秀博士学位论文 2013 华东理工大学优秀博士论文 2008 法国大使馆留学奖学金

研究领域

医学为导向的化学生物学研究，课题组主要围绕以下两方面开展基础与应用研究： 1）靶向重要生命与疾病过程的生物基（糖、多肽等）分子探针和超分子材料构建； 2）临床医学为导向的新型光学体外诊断试剂盒研发。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Dual enzyme activated fluorescein based fluorescent probe Maria L. Odyniec, Jordan E. Gardiner, Adam C. Sedgwick, Xiao-Peng He, Steven D. Bull*, Tony D. James* Front. Chem. Sci. Eng. 2019 DOI 10.1007/s11705-018-1785-9 Multivalent Glycosheets for Double Light–Driven Therapy of Multidrug-Resistant Bacteria on Wounds Xi-Le Hu, Linyang Chu, Xiaojing Dong, Guo-Rong Chen, Tingting Tang, Daijie Chen*, Xiao-Peng He*, He Tian Adv. Funct. Mater. 2019, 29, 1806986. DOI 10.1002/adfm.201806986 ESIPT-based fluorescence probe for the ratiometric detection of superoxide Luling Wu, Liyuan Liu, Hai-Hao Han, Xue Tian, Maria L. Odyniec, Lei Feng, Adam C. Sedgwick*, Xiao-Peng He, Steven D. Bull*, Tony D. James* New J. Chem. 2019, 43, 2875-2877. DOI 10.1039/c8nj05656k Fluorogenic probes for disease-relevant enzymes Junji Zhang†, Xianzhi Chai†, Xiao-Peng He*, Hae-Jo Kim*, Juyoung Yoon*, He Tian Chem. Soc. Rev. 2018, 48, 683-722. DOI 10.1039/C7CS00907K Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents Adam C. Sedgwick, Luling Wu, Hai-Hao Han, Steven D. Bull*, Xiao-Peng He*, Tony D. James*, Jonathan L. Sessler*, Ben Zhong Tang*, He Tian*, Juyoung Yoon* Chem. Soc. Rev. 2018, 47, 8842-8880. DOI 10.1039/C8CS00185E Tetraphenylethylene-based glycoclusters with aggregation-induced emission (AIE) properties as high-affinity ligands of bacterial lectins Marion Donnier-Maréchal, Shuay Abdullayev, Marvin Bauduin, Yoann Pascal, Meng-Qi Fu, Xiao-Peng He, Emilie Gillon, Anne Imberty, Eric Kipnis, Rodrigue Dessein, Sébastien Vidal* Org. Biomol. Chem. 2018, 16, 8804-8809. DOI 10.1039/C8OB02035C Fluorescence Imaging of Alzheimer’s Disease with a Flat Ensemble Formed between a Quinoline–Malononitrile AIEgen and Thin‐Layer Molybdenum Disulfide Wei‐Tao Dou†, Jing‐Jing Zhang†, Qiang Li, Zhiqian Guo, Weihong Zhu, Guo‐Rong Chen, Hai‐Yan Zhang*, Xiao‐Peng He* ChemBioChem 2018, 19, 1-6. DOI 10.1002/cbic.201800508 An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates Adam C. Sedgwick†, Wei-Tao Dou†, Jin-Biao Jiao, Luling Wu, George T Williams, A. Toby A. Jenkins, Steven D. Bull, Jonathan L. Sessler*, Xiao-Peng He*, Tony D. James*J. Am. Chem. Soc. 2018, 140, 14267-14271. DOI 10.1021/jacs.8b08457 Preferential Colonization of Osteoblasts Over Co-cultured Bacteria on a Bifunctional Biomaterial Surface Linyang Chu†, Ying Yang†, Shengbing Yang, Qiming Fan, Zhifeng Yu, Xi-Le Hu, Tony D. James*, Xiao-Peng He, Tingting Tang*Front. Microbiol. 2018, 9, 2219-2231. DOI 10.3389/fmicb.2018.02219 ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND’ biological thiols Luling Wu†, Hai-Hao Han†, Liyuan Liu, Jordan E. Gardiner, Adam C. Sedgwick, Chusen Huang*, Steven D. Bull*, Xiao-Peng He*, Tony D. James* Chem. Commun. 2018, 54, 11336-11339. DOI 10.1039/c8cc06917d “And”-based fluorescence scaffold for the detection of ROS/RNS and a second analyte Maria L. Odyniec†, Adam C. Sedgwick†*, Alexander H. Swan, Maria Weber, T. M. Simon Tang, Jordan E. Gardiner, Miao Zhang, Yun-Bao Jiang, Gabriele Kociok-Kohn, Robert B. P. Elmes, Steven D. Bull*, Xiao-Peng He*, Tony D. James* Chem. Commun. 2018, 54, 8466-8469. DOI 10.1039/c8cc04316g Photocontrolled fluorescence “double-check” bioimaging enabled by a glycoprobe-protein hybrid Youxin Fu†, Hai-Hao Han†, Junji Zhang*, Xiao-Peng He*, Ben L. Feringa, He Tian*J. Am. Chem. Soc. 2018, 140, 8671-8674. DOI 10.1021/jacs.8b05425 Glypican-3-targeted precision diagnosis of hepatocellular carcinoma on clinical sections with a supramolecular 2D imaging probe Hai-Hao Han†, Yu-Jiao Qiu†, Yuan-Yuan Shi†, Wen Wen, Xiao-Peng He*, Li-Wei Dong*, Ye-Xiong Tan*, Yi-Tao Long, He Tian, Hong-Yang Wang*Theranostics 2018, 8, 3268-3274. DOI 10.7150/thno.24711 Osteogenesis, vascularization and osseointegration of a bioactive multiphase macroporous scaffold in the treatment of large bone defects Linyang Chu, Guoqiang Jiang, Xi-Le Hu*, Tony D. James, Xiao-Peng He, Yaping Li*, Tingting Tang* J. Mater. Chem. B 2018, 6, 4197-4204. DOI 10.1039/c8tb00766g Supramolecular glyco-poly-cyclodextrin functionalized thin-layer manganese dioxide for targeted stimulus-responsive bioimaging Huan Wang, Ying Liu, Chao Xu, Xi Wang, Guo-Rong Chen, Tony D. James, Yi Zang*, Jia Li*, Xiang Ma*, Xiao-Peng He* Chem. Commun. 2018, 54, 4037-4040. DOI 10.1039/c8cc00920a The development of a novel AND logic based fluorescence probe for the detection of peroxynitrite and GSH Adam C. Sedgwick†*, Hai-Hao Han†, Jordan E. Gardiner, Steven D. Bull*, Xiao-Peng He*, Tony D. James* Chem. Sci. 2018, 9, 3672-3676. DOI 10.1039/c8sc00733k Biodegradable macroporous scaffold with nano-crystal surface microstructure for highly effective osteogenesis and vascularization Linyang Chu, Guoqiang Jiang, Xi-Le Hu, Tony D. James, Xiao-Peng He*, Yaping Li*, Tingting Tang*J. Mater. Chem. B 2018, 6, 1658-1667. DOI 10.1039/c7tb03353b Lightening Up Membrane Receptors with Fluorescent Molecular Probes and Supramolecular Materials Xiao-Peng He, He Tian* Chem 2018, 4, 246-268. DOI 10.1016/j.chempr.2017.11.006 Supramolecular Nanostructures of Structurally Defined Graphene Nanoribbons in the Aqueous Phase Yinjuan Huang, Wei-Tao Dou, Fugui Xu, Hong-Bo Ru, Qiuyu Gong, Dongqing Wu, Deyue Yan, He Tian, Xiao-Peng He*, Yiyong Mai*, Xinliang Feng Angew. Chem. Int. Ed. 2018, 57, 3366-3371. DOI 10.1002/anie.201712637 Supramolecular glycorhodamine-polymer dot ensembles for the homogeneous, fluorogenic analysis of lectins Chang-Zheng Wang, Xiao-Peng He* Carbohydr. Res. 2018, 455, 1-4. DOI 10.1016/j.carres.2017.10.021