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贾士儒,男,天津科技大学教授,博士生导师 入选国家万人计划“国家级教学名师”。 国务院第六、七届学位委员会轻工技术与工程学科评议组成员。 分别在日本大阪大学和岐阜大学获得硕士和博士学位。 2004年被聘为天津市发酵工程学科特聘教授。 现任中国化工学会生物化工专业委员会理事与技术委员会委员,全国发酵工程技术工作委员会委员,天津市专家协会会员,天津市归国人员联谊会理事,《中国酿造》和《药物生物技术》等杂志编委会编委。 长期从事发酵工程方面的科研与教学,主要研究方向为新型生物反应过程开发与研究。利用现代微生物技术,实现天然生物制品的工业化生产技术研究与传统发酵食品研究与开发,进行农副产品以其下脚料的资源化。 部分科研情况 [1]印迹交联酶聚体(离子液)介孔氧化硅杂化催化剂的制备及其在不同介质中的催化性能,国家自然科学基金项目(21676069),2017.01-2020.12 [2]利用木葡糖酸醋酐菌一步发酵合成特定网状结构细菌纤维素的基础研究,国家自然科学基金项目(21576212),2016.01-2019.12 [3]不同聚合度ε-聚赖氨酸抑菌差异性及其相关基础研究,国家自然科学基金项目,2013.01-2016.12 [4]绿色防腐剂ε-聚赖氨酸产业化示范开发,“十二五”农村领域国家科技计划课题,2011.01-2015.12 [5]微生物注塑技术生成纳米复合材料的基础研究,国家自然科学基金项目,2010.01-2012.12 [6]抗疲劳、抗缺氧功能食品基料发酵制备技术研究,军工项目子课题,2010-2015 [7]啤酒醇酯风味调控规律的研究,973项目子课题,2011-2013 [8]重要发酵工业菌种基因组研究及分子改造,十二五国家科技计划,2011-2015 [9]ε-聚赖氨酸高产菌的定向选育及其工业化研究,国家863导向项目,2006.12-2009.10 [10]不同生长模式下发状念珠藻抗逆因子及其协同作用,国家自然科学基金项目,2008.01-2010.12 [11]抗氧化食品的研究与产业化,国家“十一五”科技支撑计划项目子课题,2006.01-2010.12 [12]天然果疏粉—新型食品配料的开发,天津市农业科技成果转化与推广项目,2007.08-2009.08 [13]聚肽或多糖偶联循环发酵过程的基础研究,国家973子课题,2007.7-2012.6 [14]海产品粉末化生产关键技术,天津市科技支撑计划重点项目,2008.4-2010.3 [15]生物防腐剂ε-聚赖氨酸的研制,国家“十五”科技攻关计划项目,2004-2005; [16]界面性质与陆生蓝细菌生长活性的关系,国家自然基金项目,2004-2006; [17]利用现代生物技术改造微生物菌种与动力学研究,教育部项目,2003-2005; [18]新型生物产业开发,中日政府间合作项目,2003-2005; [19]新型天然果蔬粉生产关键技术的研究,天津市科委科技攻关计划重点项目,2005-2006; [20]发菜细胞培养及其抗病毒活性物质开发研究,,天津市科委应用基础研究重点项目,2004-2007; [21]抗缺氧高能野战食品,国家“十五”科技攻关项目子课题(2002BA904B16),2002-2005; [22]禽骨为原料生产天然肉味香精研究与开发,天津市科委攻关项目,2003-2004; [23]超临界相态下微生物反应基础研究,国家自然基金项目,2002-2004 主要学术成果 [1]贾士儒等主编、发酵工程实验教程、北京、高等教育出版社、2016 [2]贾士儒,生物反应工程原理(第四版),科学出版社,2015.08 [3]贾士儒等主编、发菜细胞培养、北京、科学出版社、2014 [4]贾士儒主编、生物防腐剂、北京、中国轻工业出版社、2009 [5]贾士儒编著、生物反应工程原理(第三版)、北京、科学出版社、2008 [6]贾士儒主编、生物工程专业实验、北京、中国轻工业出版社、2004,2010 [7]贾士儒主编、生物工艺与工程实验技术,北京、中国轻工业出版社、2002 [8]贾士儒参编、生物制药技术,北京、中国轻工业出版社、2007 [9]贾士儒参编、发酵工程关键技术发展战略研究,北京、化学工业出版社、2005 [10]贾士儒参编、生物工艺学,北京、科学出版社、2010 获奖情况 先后获得天津自然科学三等奖(2001) 天津教学成果二等奖(2001) 教育部优秀骨干教师(2002) 国家教学成果二等奖(2005) 天津市教学成果一等奖(2005) 东丽区政府科技进步二等奖(2006) 天津市科技进步三等奖(2006) 天津市科技发明二等奖(2008) 天津市教学成果二等奖(2009) 国家优秀教师(2007) 天津市教学名师(2008) 中国食品工业协会科学技术一等奖(2011) 中国轻工业联合会科学技术进步一等奖(2013) 已培养博士、硕士研究生约90人(含同等学力、工程硕士和高教教师),在学博士、硕士生约20人。

研究领域

发酵工程专业:发酵工程原理

近期论文

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1.MiaoLiu,ChengZhong*,Yu-MingZhang,Ze-MingXu,Chang-ShengQiao,Shi-RuJia*,MetabolicinvestigationinGluconacetobacterxylinusanditsbacterialcelluloseproductionunderadirectcurrentelectricfield,FrontiersinMicrobiology,2016,7,331 2.Pei-peiHan,Shi-gangShen,Hui-YanWang,Shun-yuYao,Zhi-leiTan,ChengZhong,Shi-ruJia*,ApplyingthestrategyoflightenvironmentcontroltoimprovethebiomassandpolysaccharideproductionofNostocflagelliforme,JournalofAppliedPhycology,2016,1-11 3.Xiao-NingYang,Dong-DongXue,Jia-YingLi,MiaoLiu,Shi-RuJia,Li-QiangChu,FazliWahid,Yu-MingZhang,ChengZhong*,ImprovementofAntimicrobialActivityofGrapheneOxide/BacterialCelluloseNanocompositesThroughtheElectrostaticModification,CarbohydratePolymers,2016,136:1152-1160 4.HexinLv*,FengXia,MiaoLiu,XiangganCui,FazliWahid,ShiruJia*,MetabolomicprofilingoftheastaxanthinaccumulationprocessinducedbyhighlightinHaematococcuspluvialis,AlgalResearch,2016,20,35-43 5.HexinLv*,XiangganCui,ShileiWang,ShiruJia*,MetabolicProfilingofDunaliellasalinaShiftingCultivationConditionstoNitrogenDeprivation,Metabolomics,2016,6(1) 6.TaoBo,Pei-PeiHan,Qin-ZhiSu,PingFu,Feng-ZhuGuo,Zuo-XingZheng,Zhi-LeiTan,ChengZhong,Shi-RuJia*,Antimicrobialε-poly-L-lysineinducedchangesincellmembranecompositionsandpropertiesofSaccharomycescerevisiae,FoodControl,2016,61,123-134 7.HexinLv*,XiangganCui,FazliWahid,FengXia,ChengZhong,ShiruJia*,AnalysisofthePhysiologicalandMolecularResponsesofDunaliellasalinatoMacronutrientDeprivation,PlosONE,2016,11(3) 8.Jian-DongCui*,Ya-MinZhao,Rong-LinLiu,ChengZhong,Shi-RuJia*,Surfactant-activatedlipasehybridnanoflowerswithenhancedenzymaticperformance,ScientificReport,2016,6,11. 2015年部分论文 1.Pei-peiHan,Shi-gangShen,Shi-ruJia.ComparisonofbacterialcommunitystructuresofterrestrialcyanobacteriumNostocflagelliformeinthreedifferentregionsofChinausingPCR-DGGEanalysis[J].WorldJournalofMicrobiologyandBiotechnology,2015,31(7):1061–1069. 2.Pei-peiHan,Shi-gangShen,Hui-YanWang,YingSun,Yu-jieDai,Shi-ruJia.ComparativemetabolomicanalysisoftheeffectsoflightqualityonpolysaccharideproductionofcyanobacteriumNostocflagelliforme[J].AlgalResearch,2015,9:143–150. 3.MiaoLiu,ChengZhong,Xiao-YingWu,Yu-QiaoWei,TaoBo,Pei-PeiHan,Shi-RuJia.MetabolomicprofilingcoupledwithmetabolicnetworkrevealsdifferencesinGluconacetobacterxylinusfromstaticandagitatedcultures[J].BiochemicalEngineeringJourna,2015,101:85–98. 4.JianhuaGuo,XiaolanLiu,ShiruJia.Effectofcellulase-producingbacteriaonthemetabolicactivitiesandfunctionaldiversityofbacterialcommunitiesinChineseliquorfermentinggrains[J].JournaloftheInstituteofBrewing,2015,121,(4):614-619. 5.Guo,JH(Guo,Jianhua),Jia,SR(Jia,Shiru).EffectofCellulase-ProducingBacteriaonEnzymeActivityandEsterProductioninFermentedGrainsofChineseLiquor[J].Journaloftheamericansocietyofbrewingchemists,2015,73(2):130-136. 6.JiandongCui,ShiruJia,LonghaoLiang,YaminZhao,YuxiaoFeng.MesoporousCLEAs-silicacompositemicroparticleswithhighactivityandenhancedstability[J].ScientificReports,2015,5,14203. 7.JianDongCui,ShiRuJia.Optimizationprotocolsandimprovedstrategiesofcross-linkedenzymeaggregatestechnology:currentdevelopmentandfuturechallenges[J].CriticalReviewsinBiotechnology,2015,35(1),15-28. 8.HexinLv,FengXia,ShiruJia,XiangganCui,NannanYuan.EffectsofK2HPO4ontheGrowthofNostocFlagelliformeinLiquidMediawithDifferentCarbonSources[M].AdvancesinAppliedBiotechnology.SpringerBerlinHeidelberg,2015:407-415. 9.LifangYue,YupengXiao,GuojuanSun,ShiruJia,YujieDai,XingZheng.Thesemi-continuouscultivationofNostocflagelliformecells[C].AdvancesinAppliedBiotechnology.2015,332:453-460. 10.HongleiFu,YujieDai,YueHan,LifangYue,FengXia,ShiruJia.EffectofiodineonthegrowthandqualityofNostocflagelliforme[J].LectureNotesinElectricalEngineering.2015,333:335-341. 2014年部分论文 1.ChengZhong,FeiLi,MiaoLiu,Xiao-NingYang,Hui-XiaZhu,Yuan-YuanJia,Shi-RuJia,LucianoPiergiovanni.RevealingDifferencesinMetabolicFluxDistributionsbetweenaMutantStrainandItsParentStrainGluconacetobacterxylinusCGMCC2955[J].Plosone,2014,9(6):1-9. 2.TaoBo,MiaoLiu,ChengZhong,QianZhang,Qin-ZhiSu,Zhi-LeiTan,Pei-PeiHan,andShi-RuJia.MetabolomicAnalysisofAntimicrobialMechanismsofε_x001e_Poly_x001e_L_x001e_lysineonSaccharomycescerevisiae[J].JournalofAgriculturalandFoodChemistry,2014,4454-4465. 3.ChengZhong,ZhaoZhou,Yu‐MingZhang,Shi‐RuJia,ZhuoSun,BruceE.Dale.IntegratingKineticswithThermodynamicstoStudytheAlkalineExtractionofProteinfromCaraganakorshinskiiKom.[J].BiotechnologyandBioengineering,2014,111(9):1801-1808. 4.Pei-peiHan,Shi-ruJia,YingSun,Zhi-leiTan,ChengZhong,Yu-jieDai,NingTan,Shi-gangShen.MetabolomicapproachtooptimizingandevaluatingantibiotictreatmentintheaxeniccultureofcyanobacteriumNostocflagelliforme[J].WorldJournalofMicrobiologyandBiotechnology,2014,30(9):2407-2418. 5.Jian-JunDong,Qing-LiangLi,HuaYin,ChengZhong,Jun-GuangHao,Pan-FeiYang,Yu-HongTian,Shi-RuJia.Predictiveanalysisofbeerqualitybycorrelatingsensoryevaluationwithhigheralcoholandesterproductionusingmultivariatestatisticsmethods[J].FoodChemistry,2014,161:376-82. 6.Pei-peiHan,YingSun,Xiao-yingWu,Ying-jinYuan,Yu-jieDai,Shi-ruJia.Emulsifying,Flocculating,andPhysicochemicalPropertiesofExopolysaccharideProducedbyCyanobacteriumNostocflagelliforme[J].AppliedBiochemistryandBiotechnology,2014,172(1):36-49. 7.Pei-PeiHan,YingSun,ChengZhong,Zhi-leiTan,Shi-ruJia.EffectsoflightwavelengthsonextracellularandcapsularpolysaccharideproductionbyNostocflagelliforme[J].CarbohydratePolymers,2014,105:145-151. 8.ChengZhong,ZhuoSun,ZhaoZhou,Ming-JieJin,Zhi-LeiTan,Shi-RuJia.ChemicalCharacterizationandNutritionalAnalysisofProteinIsolatesfromCaraganakorshinskiiKom.[J].JournalofAgriculturalandFoodChemistry,2014,62(14):3217–3222(SCI). 9.HexinLv,ShiruJia,YupengXiao,NannanYuanandYujieDai.GrowthcharacteristicsofNostocflagelliformeatintermittentelevatedCO2concentrations[J].PhycologicalResearch,2014,62(4):250–256(SCI). 10.LVHe-xin,JIAShi-ru,SHENShi-gang,CUIXiang-gan,YUANNan-nan.EffectofNaNO3onNostocflagelliformeGrowthunderIntermittentFlowofCO2[J].ModernFoodScienceandTechnology,2014,30(9):186-191(SCI). 11.JiandongCui,JiqiongQiu,XianweiFan,ShiruJia,ZhileiTan.Biotechnologicalproductionandapplicationsofmicrobialphenylalanineammonialyase:arecentreview[J].CriticalReviewsinBiotechnology,2014,34(3):258-268(SCI). 2013年部分论文 1.ChengZhong,Gui-CaiZhang,MiaoLiu,Xin-TongZheng,Pei-PeiHan,Shi-RuJia.MetabolicfluxanalysisofGluconacetobacterxylinusforbacterialcelluloseproduction.ApplMicrobiolBiotechnol,2013,97:6189–6199. 2.YujieDai,JingLi,ShumeiWei,NanChen,YupengXiao,ZhileiTan,ShiruJia,NannanYuan,NingTanandYijieSong.EffectoflightwithdifferentwavelengthsonNostocflagelliformecellsinliquidculture[J].JournalofMicrobiologyandBiotechnology,2013,23(4):534-538. 3.ZhenDing,ShiruJia,PeipeiHan,NannanYuan,NingTan.EffectsofcarbonsourcesongrowthandextracellularpolysaccharideproductionofNostocflagelliformeunderheterotrophichigh-cell-densityfed-batchcultures.JApplPhyool.2013,25(4):1017-1021. 4.Zhi-leiTan,Yu-QiaoWei,ShuangLiang,RanZhang,MiaoLiu,Shi-RuJia.RapidIdentificationofMicroorganismsIsolatedfromPickledVegetablesbyMALDI-TOFMassSpectrometry[J].AdvancedMaterialsResearch.2013.712-715:494-497. 2012部分论文 1.ChengZhong,RuiWang,ZhaoZhou,Shi-RuJia,Zhi-LeiTan,Pei-PeiHan.FunctionalPropertiesofProteinIsolatesfromCaraganaKorshinskiiKomExtractedbyThreeDifferentMethods.JournalofAgriculturalandFoodChemistry2012,60:10337-10342. 2.YanqingZhang,ShiruJia,WujiuZhang.Predictingaceticacidcontentinthefinalbeerusingneuralnetworksandsupportvectormachine.JournaloftheInstituteofBrewing.2012,118:361-36. 3.NingTan,Shi-RuJia,Pei-PeiHan,WeiGuo,Yu-JieDai.TheopencultureofNostocflagelliformewitha25Lopenpond.AdvancedMaterialsResearchVols.554-556(2012). 4.ShiruJia,ZhenDing,NingTan,NaWang,PeipeiHan,NannanYuan.HeterotrophicFed-batchCulturesofNostocflagelliformeandProductionofExtracellularPolysaccharides.AdvancedMaterialsResearchVols.518-523(2012):5468-5471. 5.SijunYue,JingLiu,RuiZheng,YujieDai,YuanyuanJia,ShiruJia.ThegrowthofNostocflagelliformecellsindesertsoilanditsecologicaleffects.AdvancedMaterialsResearchVols.518-523(2012):5500-5505. 6.YANLin,JIAShi-ru,ZHENGXin-tong,ZHONGCheng,LIUMiao,XUGuo-juan.Theeffectofgrowth,migrationandbacterialcellulosesynthesisofGluconacetobacterxylinusinpresenceofdirectcurrentelectricfieldcondition.AdvancedMaterialsResearchVols.550-553(2012):1108-1113. 7.ChengZhong,RuiWang,LihuaFan,Shi-RuJia,ZhaoZhou.DevelopingahighefficientprocessintegratingproteinextractionwithcellulosicethanolproductionfromCaraganaKorshinskiiKom.AdvancedMaterialsResearchVols.518-523(2012):5545-5549. 8.JinYingGuo,MingKeShi,GuoYanRen,YongYin,ShiRuJia.ResponseofNostocflagelliformecelltoHyperthermiaStress.AdvancedMaterialsResearch(Volumes518-523):614-618(2012). 9.YujieDai,NanChen,ShiruJia,NannanYuan,NingTanJingLi.PurificationofPolysaccharidefromPhotoautotrophicCultivationofNostocflagelliformeCellswithSectorRadialFlowChromatography.BiomedicalEngineeringandBiotechnology(iCBEB),2012InternationalConferenceon.2012.5:465-468. 10.TianWANG,ShiruJIA,ZhileiTAN,YujieDAI,ShuaiSONG,GuoliangWANG.Mutagenesisandselectivebreedingofahighproducingε-ploy-L-lysinestain.FrontiersofChemicalScienceandEngineeering.2012,6(2):179-183. 11.FeifeiWang,JianchunZhang,LiminHao,ShiruJia,JianmingBaandShuangNiu.OptimizationofSubmergedCultureConditionsforMycelialGrowthandExtracellularPolysaccharideProductionbyCoriolusversiolor.Bioprocessing&Biotechniques.2012,2:42(4). 2011年部分论文 [1]HuixiaZhu,ShiruJia,HongjiangYang,YuanyuanJia,LinYan,JingLi.(2011)Peparationandapplicationofbacterialcellulosesphere:anovelbiomaterial.Biotechnol.&Biotechnol.Eq.,25(1):233-2236. [2]DexiBi,ZhenXu,EwanM.Harrison,CuiTai,YiqingWei,XinyiHe,ShiruJia,ZixinDeng,KumarRajakumar,andHong-YuOu.(2011)ICEberg:aweb-basedresourceforintegrativeandconjugativeelementsfoundinBacteria.NucleicAcidsResearch,1-6.doi:1093/nar/gkr846. [3]HuiXiaZhu,ShiruJia,TongWang,HongjiangYang,JingLi,LinYan,ChengZhong..(2011)BiosynthesisofsphericalFe3O4/bacterialcellulosenanocompositesasadsorbentsforheavymetalions.CarbohydratePolymers,86(4):1558-1564. [4]JieZhang,JonJurriaanvanAartsen,XiaofeiJiang,YuchengShao,CuiTai,XinyiHe,ZhileiTan,ZixinDeng,ShiruJia,KumarRajakumar,Hong-YuOu.(2011)ExpansionoftheknownKlebsiellapneumoniaespeciesgenepoolbycharacterizationofnovelalienDNAislandsintegratedintotmRNAgenesites.JournalofMicrobiologicalMethods,84(2),283-289. [5]XueFengChen,Shi-RuJia,YueWangandNingWang.(2011)BiologicalcrustofNostocflagelliforme(cyanobacteria)onsandbedmaterials[J].JApplPhycol,23:67~71. 2010年部分论文 [1]Shirujia,BaoqingFan,YujieDai,GuoliangWang,PengPeng,YuanyuanJia.Fractionationandcharacterizationofe-poly-L-lysinefromStreptomycesalbulusCGMCC1986[J].FoodScienceandBiotechnology,2010,19(2):361-366. [2]YurongGao,ShiruJia,QiangGao,ZhileiTan.AnovelbacteriocinwithabroadinhibitoryspectrumproducedbyLactobacillussakeC2,isolatedfromtraditionalChinesefermentedcabbage[J].FoodControl,2010,21(1):76-81. [3]WeihuaTang,ShiruJia,YuanyuanJia,HongjiangYang.Theinfluenceoffermentationconditionsandpost-treatmentmethodsonporosityofbacterialcellulosemembrane[J].WorldJMicrobiolBiotechnol,2010,26(1):125-131. [4]XuefengChen,ShiruJia,SijunYue,NingWang,ChengtaoLi,YueWang.Effectofsolidbed-materialsonvegetativecellsofNostocflagelliforme[J].JApplPhycol,2010,22(3):341-347. [5]ChangshengQiao,ShiruJia,YujieDai,RuiWang,AiyouSun.Trehalosebiosynthesisenhancementforsixyeaststrainsunderpressurizedculture[J].ApplBiochemBiotechnol,2010,160:613-620. [6]HaifengYu,ShiruJia,YujieDai.AccumulationofExopolysaccharidesinliquidsuspensioncultureofNostocflagelliformecells[J].ApplBiochemBiotechnol,2010,160:552-560. [7]LiminHao,XinhuiXing,ZhengLi,JianchunZhang,JinxuSun,ShiruJia,ChangshengQiao,TianyiWu.OptimizationofeffectfactorsformycelialgrowthandexopolysaccharideproductionbySchizophyllumcommune[J].ApplBiochemBiotechnol,2010,160(2):621-631. 2009年部分论文 [1]AnovelbacteriocinwithabroadinbitoryspectrumproducedbyLactobacillussakeC2,isolatedfromtraditionalChinesefermentedcabbage.FoodControl,2010,21(1):76-81. [2]GrowthcharacteristicsofthecyanobacteriumNostocflagelliformeinphotoautotrophic,mixotrophicandheterotrophiccultivation.JApplPhycol,2009,21(1):127-133. [3]ProductionofhydrocortisonebyAbsidiacoeruleainmoderatepressurebioconversionsystem.KoreanJChemEng,2009,26(4):1084-1089. [4]Effectofsolidbed-materialsonvegetativecellsofNostocflagelliforme.JApplPhycol,2009,DIO:10.1007/s10811-009-9464-3. [5]ComputationalStudyontheConformationandVibrationFrequenciesofβ-Sheetofε-PolylysineinVacuum,Int.J.Mol.Sci,2009,10(8):3358-3370. [6]TheinfluenceoffermentationConditionsandpost-treatmentmethodsonporosityofbacterialcellulosemembrane.WorldJMicrobiolBiotechnol,2009,DIO:10.1007/s11274-009-0151-y 2008年部分论文 [1]Influenceofaminoacids,organicsolventsandsurf-actantsforphenylalanineammonialyaseactivityinrecombinantEscherichi-a.Coli.LettersinAppliedMicrobiology,2008,46(6):631-635. [2]Rapiddeterminationoflow-levelsulfurcom-poundsinbeerbyheadspacegaschromatographywithapulsedflamepho-tometricdetector.J.Am.Soc.Brew.Chem.2008,66(3):188-191. [3]ProductionofL-phenylalaninefromtrans-cinnamicacidsbyhigh-levelexpressionofphenylalanineammonialya-segenefromRhodosporidiumtoruloidesinEscherichiacoli.BiochemicalEngineeringJournal,2008,42(3):193-197. [4]GrowthcharacteristicsofthecyanobacteriumN-ostocflagelliformeinphotoautotrophic,mixotrophicandheterotrophicculti-vation.JournalofAppliedPhycology2008(onlinefirst)DOI:10.1007/s10811-008-9341-5. 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学术兼职

现任中国化工学会生物化工专业委员会理事与技术委员会委员,全国发酵工程技术工作委员会委员,天津市专家协会会员,天津市归国人员联谊会理事,《中国酿造》和《药物生物技术》等杂志编委会编委。

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