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“A General Strategy for the Synthesis of Rare Sugars via Ru(II)-catalyzed and Boron-mediated Selective Epimerization of 1,2-trans-diols to 1,2-cis-diols” Li, X.; Wu, J.; and Tang, W.* J. Am. Chem. Soc. 2022, in press.
“Streamlined Iterative Assembly of Thio-oligosaccharides by Aqueous S-Glycosylation of Diverse Deoxythio Sugars” Peng, W.; Jia, P.; Fan, Q.; McCarty, B. J. and Tang, W.* ChemSusChem. 2021, in press,
“In Silico Modeling and Scoring of PROTAC-Mediated Ternary Complex Poses” Liao, J.; Nie, X.; Unarta, I. C.; Ericksen, S. S.*; and Tang, W.* ChemRxiv. 2021, DOI: 10.26434/chemrxiv-2021-ldzzz-v3.
“Energy Decomposition Analysis Reveals the Nature of Lone Pair−π Interactions with Cationic π Systems in Catalytic Acyl Transfer Reactions” Hao, H.; Qi, X.; Tang, W.* and Liu, P.* Org. Lett. 2021, 23, 4411–4414.
“Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins” Zhou, Y.; Teng, P.; Montgomery, N. T.; Li, X.; and Tang, W.* ACS Cent. Sci, 2021, 7, 499-506.
“Evaluation of the binding affinity of E3 ubiquitin ligase ligands by cellular target engagement and in-cell ELISA assay” Yang, K.; Zhou, Y.; Roberts, R. L.; Nie, X.; Tang, W.* Star Protocols 2021, 2, 100288.
“A neuroanatomical mechanism linking perinatal TCDD exposure to lower urinary tract dysfunction in adulthood” Turco, A. E.; Oakes, S. R.; Stietz, K. P. K. Dunham, C. L.; Joseph, D. B.; Chathurvedula, T. S.; Girardi, N. M.; Schneider, A. J.; Gawdzik, J.; Sheftel, C. M.; Wang, P.; Wang, Z.; Bjorling, D. E.; Ricke, W. A.; Tang, W.; Hernandez, L. L.; Keast, J. R.; Bonev, A. D.; Grimes, M. D.; Strand, D. W.; Tykocki, N. R.; Tanguay, R. L.; Peterson, R. E.; Vezina, C. M. Dis. Models Mech. 2021, 14, dmm049068.
“Development of MDM2 Degraders Based on Ligands Derived from Ugi Reactions:Lessons and Discoveries” Wang, B.; Liu, J.; Tandon, I.; Wu, S.; Teng, P.; Liao, J.; and Tang, W.* Eur. J. Med. Chem. 2021, 219, 113425.
“A dancing nickel in asymmetric catalysis: Enantioselective synthesis of boronic esters by 1,1-addition to terminal alkenes” McCarty, B. J. and Tang, W.* Green Syn. Cat. 2021, 2, 1-3.
“Transition Metal-Catalyzed Selective Carbon−Carbon Bond Cleavage of Vinylcyclopropanes in Cycloaddition Reactions” Wang, J.; Blaszczyk, S. A.; Li, X.;* and Tang, W.* Chem. Rev. 2021, 121, 110-139.
“A marine microbiome antifungal targets urgent-threat drug-resistant fungi” Zhang, F.; Zhao, M.; Braun, D. R.; Ericksen, S. S.; Piotrowski, J. S.; Nelson, J.; Peng, J.; Ananiev, G. E. Chanana, S.; Barns, K.; Fossen, J.; Sanchez, H.; Chevrette, M. G.; Guzei, I. A.; Zhao, C.; Guo, L.; Tang, W.; Currie, C. R.; Rajski, S. R.; Audhya, A.; Andes, D. R.; Bugni, T. S. Science, 2020, 370 (issue 6519), 974-978.
“From Methylene Bridged Diindole to Carbonyl Linked Benzimidazoleindole: Development of Potent and Metabolically Stable PCSK9 Modulators” Xie, H.;‡ Yang, K.;‡ Winston-McPherson, G. N.; Stapleton, D. S.; Keller, M. P.; Attie, A. D.; Smith, K. A.; and Tang, W.* Eur. J. Med. Chem. 2020, 206, 112678-112692. (‡Equal Contribution)
“Mild Cu(OTf)2-mediated C-glycosylation with Chelation-Assisted Picolinate as a Leaving Group” Ye, W.;‡ Stevens, C. M.;‡ Wen, P.;‡ Simmons, C. J.; and Tang, W.* J. Org. Chem. 2020, 85, 16218–16225. (‡Equal Contribution) (Special Issue on A New Era of Discovery in Carbohydrate Chemistry)
“A Cell-based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders” Yang, K.;‡ Zhao, Y.;‡ Nie, X.; Wu, H.; Wang, B.; Almodovar-Rivera, C. M.; Xie, H.;* Tang, W.* Cell Chem. Biol. 2020, 27, 866-876. (‡Equal Contribution)
“Two-stage Strategy for Development of Proteolysis Targeting Chimeras and its Application for Estrogen Receptor Degraders” Roberts, B. L.;‡ Ma, Z.-X.;‡ Gao, A.; Leisten, E. D.; Yin, D.; Xu, W.; and Tang, W.* ACS Chem. Biol. 2020, 15, 1487–1496. (‡Equal Contribution)
“Chemical Synthesis and Biological Application of Modified Oligonucleotides” Glazier, D. A.;‡ Liao, J.;‡ Roberts, B. L.;‡ Li, X.; Yang, K.; Stevens, C. M.; and Tang, W.* Bioconjugate Chem. 2020, 31, 1213-1233. (‡Equal Contribution)
“Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel–Lindau (VHL) E3 Ubiquitin Ligase” Yang, K.;‡ Wu, H.;‡ Zhang, Z.; Leisten, E. G.; Nie, X.; Liu, B.; Wen, Z.; Zhang, J.; Cunningham, M. D. and Tang, W.* ACS Med. Chem. Lett. 2020, 11, 575-581. (‡Equal Contribution)
“Synthesis of Glycosyl Chlorides and Bromides by Chelation Assisted Activation of Picolinic Esters under Mild Neutral Conditions” Wen, P.;‡ Simmons, C. J.;‡ Ma, Z.-X.; Blaszczyk, S. A.; Balzer, P. G.; Ye, W.; Duan, X.; Wang, H.-Y.; Yin, D.; Stevens, C. M.; and Tang, W.* Org. Lett. 2020, 22, 1495-1498. (‡Equal Contribution)
“Synthesis and Biological Evaluation of FICZ Analogues as Agonists of Aryl Hydrocarbon Receptor” Wu, H.;‡ Liu, B.;‡ Yang, K.;‡ Winston-McPherson, G. N.; Leisten, E. D.; Vezina, C. M.; Ricke, W. A.; Peterson, R. E.; and Tang, W.* Bioorg. Med. Chem. Lett. 2020, 30, 126959. (‡Equal Contribution)
“Rhodium-Catalyzed (5 + 2) and (5 + 1) Cycloadditions Using 1,4-Enynes as Five-Carbon Building Blocks” Blaszczyk, S. A.; Glazier, D. A.; and Tang, W.* Acc. Chem. Res. 2020, 53, 231-243.