Poor understanding of the pathophysiological mechanisms involved in Haemophilia is a major obstacle in accessing effective haemophilia disease management. Haemophilia is a life-frightening bleeding problem in which there are repeated bleeding episodes. Various approaches have been used, involves clotting factor replacement therapy for effective bleeding control in Haemophilia. Current advancements in the management of patients with haemophilia include altered pharmacokinetics clotting factor concentrates for better prophylaxis and management of haemophilia. This review sums up the prophylactic treatment, novel production techniques, other treatment techniques and the present position of gene therapy in the treatment of haemophilia.

对血友病所涉及的病理生理机制的了解不足，是获得有效血友病疾病管理的主要障碍。血友病是一个令人恐惧的出血问题，其中反复出现出血事件。为了有效控制血友病中的出血，已经使用了各种方法，包括凝血因子替代疗法。血友病患者管理方面的最新进展包括改变药代动力学凝血因子浓缩物，以更好地预防和管理血友病。这篇综述总结了预防性治疗，新颖的生产技术，其他治疗技术以及基因治疗在血友病治疗中的当前地位。