Tuning the optical properties of graphene quantum dots for biosensing and bioimaging,Journal of Materials Chemistry B

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Tuning the optical properties of graphene quantum dots for biosensing and bioimaging
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2018-04-13 00:00:00 , DOI: 10.1039/c8tb00428e
Xin Hai _{1,

2,

3,

4,

5} , Ji Feng _{1,

2,

3,

4,

5} , Xuwei Chen _{1,

2,

3,

4,

5} , Jianhua Wang _{1,

2,

3,

4,

5}

Affiliation

Due to their low toxicity, excellent biocompatibility and attractive optical properties, graphene quantum dots (GQDs) have attracted significant attention in the analytical and biological fields. The controllable intrinsic nature of graphene nano-sheets, e.g., size, layer, edge state or shape, offer the chance to fabricate GQDs with tunable photoluminescence behaviors. Carboxylic moieties on the surface and edges of GQDs can provide efficient reactive sites for interaction with various polymeric, organic, inorganic and biological species. This not only provides the chance to tune the optical properties of GQDs via facile chemical approaches such as surface modulation and doping, but also makes GQDs eco-friendly alternatives to replace the traditional fluorescent probes in biological assays. This review highlights new insights into the various strategies for tuning the optical features of GQDs, and their employment as attractive and powerful probes for bio-sensing/imaging. The challenges and future perspectives in the related fields are discussed.

中文翻译：

调整石墨烯量子点的光学特性以用于生物传感和生物成像

由于其低毒性，出色的生物相容性和诱人的光学性能，石墨烯量子点（GQD）在分析和生物领域引起了极大的关注。石墨烯纳米片的可控制的固有性质，例如尺寸，层，边缘状态或形状，为制造具有可调光致发光行为的GQD提供了机会。GQD表面和边缘上的羧基部分可提供有效的反应位点，以与各种聚合，有机，无机和生物物种相互作用。这不仅提供了机会以调谐GQDs的光学性质通过简便的化学方法（例如表面调制和掺杂），也使GQD成为生态友好的替代品，以取代生物测定中的传统荧光探针。这篇综述重点介绍了各种用于调节GQD光学特性的策略的新见解，以及它们作为生物传感/成像的有吸引力且功能强大的探针的用途。讨论了相关领域中的挑战和未来前景。

更新日期：2018-04-13

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