Both obesity and atrial fibrillation (AF) are increasing in epidemic proportions, and both increase the prevalence of cardiovascular disease events. Obesity has adverse effects on cardiovascular hemodynamics and cardiac structure and function, and increases the prevalence of AF, partly related to electroanatomic remodeling in obese patients. However, numerous studies, including in AF, have demonstrated an obesity paradox, where overweight and obese patients with these disorders have a better prognosis than do leaner patients with the same degree of severity of cardiovascular disease/AF. In this paper, the authors discuss special issues regarding AF in obesity, as well as the evidence that despite the presence of an obesity paradox, there are benefits of weight loss, physical activity/exercise training, and increases in cardiorespiratory fitness on the prognosis of obese patients with AF.

中文翻译：

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肥胖和心房颤动的患病率、发病机制和预后

肥胖和心房颤动 (AF) 的流行比例都在增加，并且都增加了心血管疾病事件的发生率。肥胖对心血管血流动力学和心脏结构和功能有不利影响，并增加 AF 的患病率，部分与肥胖患者的电解剖重构有关。然而，包括 AF 在内的许多研究已经证明了肥胖悖论，即患有这些疾病的超重和肥胖患者比具有相同严重程度心血管疾病/AF 的瘦弱患者具有更好的预后。在这篇论文中，作者讨论了肥胖中 AF 的特殊问题，以及证据表明尽管存在肥胖悖论，但减肥、体育锻炼/运动训练仍有好处，