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Cabotegravir and rilpivirine long acting injectables in a pregnant woman living with HIV
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2024-05-04 , DOI: 10.1093/cid/ciae242
Lena van der Wekken-Pas 1 , Fabian Weiss 2 , Charlotte Simon-Zuber 2 , Rena Sebisch 2 , Carmen Wiese 3 , Elisabeth van Leeuwen 4 , David Burger 1 , Angela Colbers 1
Affiliation  

This case report describes bimonthly LAI CAB/RPV prior to and throughout pregnancy. CAB concentration was comparable to non-pregnant individuals, RPV was 70-75% lower. No virologic failure orvertical transmission occurred. Despite placental transfer, no congenital malformations were noted. Bimonthly CAB/RPV LAI may not be suitable for pregnant women and monitoring of exposed infants is warranted.

中文翻译:

卡博特韦和利匹韦林长效注射剂用于感染艾滋病毒的孕妇

本病例报告描述了怀孕前和整个怀孕期间每两个月一次的 LAI CAB/RPV。 CAB 浓度与非怀孕个体相当,RPV 低 70-75%。没有发生病毒学失败或垂直传播。尽管进行了胎盘移植,但未发现先天性畸形。每两个月一次的 CAB/RPV LAI 可能不适合孕妇,因此有必要对暴露的婴儿进行监测。
更新日期:2024-05-04
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