当前位置: X-MOL 学术Clin. Infect. Dis. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Cumulative tenofovir exposure among patients with human immunodeficiency virus/hepatitis B co-infection with differential viral suppression
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2024-05-04 , DOI: 10.1093/cid/ciae241
Helen L Zhang 1 , Meredith Mock 2 , Lane Bushman 3 , Peter L Anderson 3 , Jennifer J Kiser 3 , Susanna Naggie 4
Affiliation  

This case-control study explored cumulative tenofovir exposure among patients with HIV/HBV co-infection with HIV viral suppression. Among patients taking tenofovir disoproxil fumarate, median TFV-DP levels in dried blood spots were ∼3-fold lower among patients with incomplete HBV viral suppression (n=4) compared to those with complete suppression (n=5) (516 vs.1456 fmol/punch).

中文翻译:

人类免疫缺陷病毒/乙型肝炎混合感染患者中不同病毒抑制的累积替诺福韦暴露量

这项病例对照研究探讨了 HIV/HBV 合并感染且抑制 HIV 病毒的患者中替诺福韦的累积暴露量。在服用富马酸替诺福韦二吡呋酯的患者中,与完全抑制 HBV 病毒的患者 (n=5) 相比,不完全抑制 HBV 病毒的患者 (n=4) 干血斑中的中位 TFV-DP 水平低约 3 倍(516 比 1456) fmol/冲)。
更新日期:2024-05-04
down
wechat
bug