Thiazolidinediones (TZDs) are potent insulin-sensitizing drugs, but their use is accompanied by adverse side-effects. Rohm et al. now report that TZD-stimulated macrophages release miR-690-containing vesicles that improve insulin sensitization and bypass unwanted side-effects.

中文翻译：

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巨噬细胞囊泡在抗糖尿病药物作用中的作用

噻唑烷二酮类药物 (TZD) 是有效的胰岛素增敏药物，但其使用会带来不良副作用。罗姆等人。现在报告说，TZD 刺激的巨噬细胞释放含有 miR-690 的囊泡，可改善胰岛素敏感性并绕过不需要的副作用。