The mechanisms that drive cancer cachexia are unclear. Adipocyte activation of GPR81 by high levels of lactate is now shown to drive adipose tissue browning, thermogenesis and a loss of body weight in mouse models of cancer.

中文翻译：

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废物在浪费中发挥意想不到的作用

导致癌症恶病质的机制尚不清楚。现在研究表明，高水平的乳酸对脂肪细胞 GPR81 的激活会导致小鼠癌症模型中的脂肪组织褐变、产热和体重减轻。