In a new study published in Nature, researchers have investigated the role of tumour-associated macrophages (TAMs) in pancreatic cancer. It has previously been shown that pancreatic ductal adenocarcinoma (PDAC) tumours are infiltrated by TAMs linked to pathogenic inflammation. “We were particularly interested in understanding how inflammation promotes pancreatic cancer, and what was the role of macrophages in this process,” say Nicoletta Caronni and Renato Ostuni, corresponding authors of the study.

中文翻译：

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肿瘤相关巨噬细胞和胰腺癌：炎症循环

在《自然》杂志上发表的一项新研究中，研究人员研究了肿瘤相关巨噬细胞（TAM）在胰腺癌中的作用。此前已有研究表明，胰腺导管腺癌 (PDAC) 肿瘤被与致病性炎症相关的 TAM 浸润。该研究的通讯作者 Nicoletta Caronni 和 Renato Ostuni 表示：“我们特别感兴趣的是了解炎症如何促进胰腺癌，以及巨噬细胞在这一过程中的作用。”