Wound healing is a long-term, multi-stage biological process that mainly includes haemostatic, inflammatory, proliferative and tissue remodelling phases. Controlling infection and inflammation and promoting tissue regeneration can contribute well to wound healing. Smart biomaterials offer significant advantages in wound healing because of their ability to control wound healing in time and space. Understanding how biomaterials are designed for different stages of wound healing will facilitate future personalized material tailoring for different wounds, making them beneficial for wound therapy. This review summarizes the design approaches of biomaterials in the field of anti-inflammatory, antimicrobial and tissue regeneration, highlights the advanced precise control achieved by biomaterials in different stages of wound healing and outlines the clinical and practical applications of biomaterials in wound healing.

中文翻译：

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用于伤口愈合的定制生物医学材料。

伤口愈合是一个长期、多阶段的生物过程，主要包括止血、炎症、增殖和组织重塑阶段。控制感染和炎症并促进组织再生可以很好地促进伤口愈合。智能生物材料由于能够在时间和空间上控制伤口愈合，因此在伤口愈合方面具有显着的优势。了解生物材料如何针对伤口愈合的不同阶段进行设计，将有助于未来针对不同伤口定制个性化材料，使其有益于伤口治疗。该综述总结了生物材料在抗炎、抗菌和组织再生领域的设计方法，重点介绍了生物材料在伤口愈合不同阶段所实现的先进精确控制，概述了生物材料在伤口愈合中的临床和实际应用。