INTRODUCTION Hepatic encephalopathy (HE) is prevalent and is associated with increased morbidity and mortality among patients with cirrhosis. On October 1, 2022, a new, specific International Classification of Diseases-10 code for HE, K76.82, was introduced. We aimed to analyze the diagnostic accuracy of K76.82. METHODS Diagnostic performance of K76.82 for HE (sensitivity, specificity, positive predictive ratio, and negative predictive ratio) was evaluated in 2 large health systems compared with lactulose, rifaximin, and K72.90. RESULTS A total of 2,483 patients were analyzed. The combination term "lactulose or rifaximin" showed the highest sensitivity of >98% while K76.82 demonstrated a specificity of >87% in all cohorts. DISCUSSION Although K76.82 is promising, the combination term "lactulose or rifaximin" identified patients with HE more accurately.

中文翻译：

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ICD-10 代码 K76.82 对肝硬化患者肝性脑病的诊断性能。

简介 肝性脑病 (HE) 很常见，并且与肝硬化患者发病率和死亡率增加相关。2022 年 10 月 1 日，引入了 HE 的新的特定国际疾病分类 10 代码 K76.82。我们的目的是分析 K76.82 的诊断准确性。方法 与乳果糖、利福昔明和 K72.90 相比，在 2 个大型卫生系统中评估了 K76.82 对 HE 的诊断性能（敏感性、特异性、阳性预测比和阴性预测比）。结果 总共分析了 2,483 名患者。组合术语“乳果糖或利福昔明”显示出 >98% 的最高敏感性，而 K76.82 在所有队列中显示出 >87% 的特异性。讨论 尽管 K76.82 有希望，但组合术语“乳果糖或利福昔明”可以更准确地识别 HE 患者。