Background The epidemiological data on post-burn growth, body composition and motor development is ambiguous and scattered. The aim of this systematic review was therefore to summarize the current body of evidence on post-burn growth, body composition and motor development in children. Methods A literature search was conducted in PubMed, EMBASE and Web of Science up to March 2021. We considered observational studies that reported (1) metrics on weight, height, body composition, bone mineral content, bone mineral density or motor development, in (2) paediatric burn patients and (3) published in a peer-reviewed journal. Results A total of 16 studies were included. Each of the included studies used quantitative methods, but with differing methodology: prospective cohort studies (n = 8), retrospective chart reviews (n = 3), case–control studies (n = 2), cross sectional studies (n = 2) and a retrospective cohort study (n = 1). When combined, the included studies represented 2022 paediatric burn patients, with a mean age of 7.7 (±3.2) years. The average burn size was 52.8% (±12.7) of the total body surface area. Identified outcome measures included weight (n = 12), height (n = 7), muscular strength (n = 4), bone mineral content (n = 5), bone mineral density (n = 5), body mass index (n = 3), fat mass (n = 5), lean body mass (n = 7) and fine and gross motor development (n = 1). Conclusions Following an initial decline, patients’ growth and motor development started to recover during the first or second year post-burn. Nonetheless, burns may have a profound and prolonged effect on the paediatric burn patients’ muscular strength, bone mineral content and lean body mass. It should be noted that the vast majority of studies included only patients with burns covering ≥30% total body surface area. The evidence presented in this review may thus not be representative of the whole paediatric burn population.

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严重烧伤后儿童的生长和运动发育：系统评价

背景 关于烧伤后生长、身体成分和运动发育的流行病学数据不明确且分散。因此，本系统评价的目的是总结当前有关儿童烧伤后生长、身体成分和运动发育的证据。方法 在 PubMed、EMBASE 和 Web of Science 中进行了截至 2021 年 3 月的文献检索。我们考虑了报告 (1) 体重、身高、身体成分、骨矿物质含量、骨矿物质密度或运动发育指标的观察性研究，（ 2) 儿科烧伤患者；(3) 在同行评审期刊上发表。结果共纳入16项研究。每项纳入的研究均采用定量方法，但方法不同：前瞻性队列研究 (n = 8)、回顾性图表审查 (n = 3)、病例对照研究 (n = 2)、横断面研究 (n = 2)和一项回顾性队列研究（n = 1）。合并后，纳入的研究代表了 2022 名儿童烧伤患者，平均年龄为 7.7 (±3.2) 岁。平均烧伤面积占全身表面积的 52.8% (±12.7)。确定的结果指标包括体重 (n = 12)、身高 (n = 7)、肌肉力量 (n = 4)、骨矿物质含量 (n = 5)、骨矿物质密度 (n = 5)、体重指数 (n = 3)、脂肪量 (n = 5)、去脂体重 (n = 7) 以及精细和粗大运动发育 (n = 1)。结论 在最初的衰退之后，患者的生长和运动发育在烧伤后的第一年或第二年开始恢复。尽管如此，烧伤可能对儿童烧伤患者的肌肉力量、骨矿物质含量和去脂体重产生深远而长期的影响。值得注意的是，绝大多数研究仅纳入烧伤面积≥30%全身表面积的患者。因此，本综述中提供的证据可能无法代表整个儿童烧伤人群。